Yang JS, Xu ZY, Chen FX, Wang MR, Fan XL, He BS. Diagnostic value of dual-energy computed tomography in irreversible transmural intestinal necrosis in patients with acute occlusive mesenteric ischemia. World J Gastrointest Surg 2025; 17(7): 105956 [DOI: 10.4240/wjgs.v17.i7.105956]
Corresponding Author of This Article
Bo-Sheng He, MD, PhD, Department of Radiology, The Second Affiliated Hospital of Nantong University, No. 666 Shengli Road, Nantong 226001, Jiangsu Province, China. boshenghe@126.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Surg. Jul 27, 2025; 17(7): 105956 Published online Jul 27, 2025. doi: 10.4240/wjgs.v17.i7.105956
Diagnostic value of dual-energy computed tomography in irreversible transmural intestinal necrosis in patients with acute occlusive mesenteric ischemia
Ju-Shun Yang, Fei-Xiang Chen, Mei-Rong Wang, Xiao-Le Fan, Bo-Sheng He, Department of Radiology, The Second Affiliated Hospital of Nantong University, Nantong 226001, Jiangsu Province, China
Zhen-Yu Xu, Department of Ultrasonography, The Second People’s Hospital of Nantong, Nantong 226002, Jiangsu Province, China
Author contributions: Yang JS and He BS were responsible for design of the study and reviewed the manuscript; Yang JS drafted the manuscript; Xu ZY, Chen FX, and Wang MR performed data collection and analysis; Yang JS and Fan XL prepared the figures and tables; He BS were responsible for revising manuscript; and all authors have read and approved the final manuscript.
Supported by The Project of Nantong City Health Committee, No. MS2023027 and WKZL2018017; The “333” Talent Funding Project of Jiangsu Province, No. BRA2020198; The Project of Jiangsu Provincial Health Commission, No. ZD2021059; and The Youth Research Fund of Nantong Municipal Health Commission, No. QNZ2023027.
Institutional review board statement: The study was approved by the ethics committee of the Second Affiliated Hospital of Nantong University (No. 2021KT154).
Informed consent statement: The need for patient consent was waived due to the retrospective nature of the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: All data generated or analyzed during this study were available from the corresponding author Bo-Sheng He upon reasonable request.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Bo-Sheng He, MD, PhD, Department of Radiology, The Second Affiliated Hospital of Nantong University, No. 666 Shengli Road, Nantong 226001, Jiangsu Province, China. boshenghe@126.com
Received: February 13, 2025 Revised: March 29, 2025 Accepted: May 29, 2025 Published online: July 27, 2025 Processing time: 161 Days and 8.4 Hours
Core Tip
Core Tip: Acute occlusive mesenteric ischemia is an intestinal ischemic injury caused by sudden interruption of intestinal blood supply. If not treated promptly, acute occlusive mesenteric ischemia usually develops into irreversible transmural intestinal necrosis (ITIN). Accurate diagnosis of ITIN is challenging because of its non-specific clinical manifestations. Currently, there is limited research on predicting ITIN using dual energy computed tomography (DECT). We use DECT objective parameters including iodine concentration and virtual monoenergetic imaging to quantify the degree of intestinal wall ischemia, and then evaluate their predictive performance for ITIN. The results demonstrated that DECT quantitative parameters can provide important information about whether ITIN occurs.
