Copyright
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. May 27, 2025; 17(5): 103758
Published online May 27, 2025. doi: 10.4240/wjgs.v17.i5.103758
Published online May 27, 2025. doi: 10.4240/wjgs.v17.i5.103758
Efficacy of reinforcing sutures in preventing anastomotic leakage after surgery for rectal cancer: A systematic review and metaanalysis
Zi-Xuan Zhuang, Yang Zhang, Xu-Yang Yang, Zi-Qiang Wang, Xiang-Bing Deng, Ming-Ming Zhang, Colorectal Cancer Center, Department of General Surgery, West China Hospital of Sichuan University, Chengdu 610041, Sichuan Province, China
Co-corresponding authors: Xiang-Bing Deng and Ming-Ming Zhang.
Author contributions: Zhuang ZX contributed to the design and implementation of the study and the writing of the manuscript; Zhang Y and Yang XY contributed to the statistical analyses and the writing of the manuscript; Deng XB contributed to the design of the study and the revision of the manuscript; Wang ZQ contributed to the performance of the research; Deng XB and Zhang MM contributed to the quality and professional revision, and contributed equally as co-corresponding authors; Zhang MM contributed to the quality and professional revision and the writing of the manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ming-Ming Zhang, Professor, Colorectal Cancer Center, Department of General Surgery, West China Hospital of Sichuan University, No. 37 Guoxue Lane, Chengdu 610041, Sichuan Province, China. zhangmm@scu.edu.cn
Received: November 29, 2024
Revised: February 25, 2025
Accepted: March 24, 2025
Published online: May 27, 2025
Processing time: 174 Days and 22.4 Hours
Revised: February 25, 2025
Accepted: March 24, 2025
Published online: May 27, 2025
Processing time: 174 Days and 22.4 Hours
Core Tip
Core Tip: This extensive systematic review rigorously evaluates the effectiveness and safety of trans-anal versus intracorporeal reinforcement sutures in low anterior resection for rectal cancer, offering the most robust methodological appraisal to date. Through heterogeneity assessment, sensitivity and subgroup analyses, and publication bias evaluation, it strengthens evidence quality, addresses outcome variability, and underscores clinical implications. Results inform surgical decision-making by comparing anastomotic leakage risks, postoperative morbidity, and technical feasibility, advocating for standardized practices to optimize colorectal surgical outcomes.