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Retrospective Study
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Dec 27, 2025; 17(12): 112780
Published online Dec 27, 2025. doi: 10.4240/wjgs.v17.i12.112780
Effects of early activity intervention on intestinal motility recovery in patients after colorectal cancer surgery
Xiu-Lian Zhang, Ai-Ping Lin, Tian-Sheng Lin, You-Qing Huang
Xiu-Lian Zhang, Ai-Ping Lin, Department of Colorectal Tumor Surgery, The First Affiliated Hospital of Xiamen University, Xiamen 361003, Fujian Province, China
Tian-Sheng Lin, Department of Gastrointestinal Oncologic Surgery, The First Affiliated Hospital of Xiamen University, Xiamen 361003, Fujian Province, China
You-Qing Huang, Department of Hepatobiliary, Pancreatic and Vascular Surgery, The First Affiliated Hospital of Xiamen University, Xiamen 361003, Fujian Province, China
Co-first authors: Xiu-Lian Zhang and Ai-Ping Lin.
Co-corresponding authors: Tian-Sheng Lin and You-Qing Huang.
Author contributions: Zhang XL and Lin AP contributed equally as co-first authors to study design, patient recruitment, data collection, statistical analysis, and manuscript preparation; Lin TS and Huang YQ served as co-corresponding authors, contributed to study conceptualization, supervision, data interpretation, manuscript revision, and funding acquisition. All authors participated in the critical review of the manuscript and approved the final version for publication.
Institutional review board statement: This retrospective study was approved by the Ethics Committee of the First Affiliated Hospital of Xiamen University, approval No.[2023]KY-005.
Informed consent statement: Because this study involved retrospective analysis of de-identified routine clinical data and posed minimal risk to participants, the requirement for signed informed consent was waived by the Ethics Committee of the First Affiliated Hospital of Xiamen University.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: De-identified data underlying the findings of this study are available from the corresponding author upon reasonable request and with permission of the First Affiliated Hospital of Xiamen University.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: You-Qing Huang, BSc, Department of Hepatobiliary, Pancreatic and Vascular Surgery, The First Affiliated Hospital of Xiamen University, No. 55 Zhenhai Road, Siming District, Xiamen 361003, Fujian Province, China. 13695002565@163.com
Received: August 19, 2025
Revised: September 25, 2025
Accepted: November 13, 2025
Published online: December 27, 2025
Processing time: 127 Days and 18.1 Hours
Core Tip

Core Tip: This retrospective study demonstrates that systematic early activity intervention following colorectal cancer surgery significantly accelerates intestinal motility recovery (19.3 hours faster first flatus) while reducing complications by 62.5%. The protocol progresses from passive bed exercises within 6 hours to walking after 48 hours post-surgery. Beyond physiological improvements, early mobilization enhanced pain management, improved enteral nutrition tolerance (90.0% vs 72.5%), and reduced nursing workload by 18.6%. The intervention also improved patient psychological well-being and sleep quality. As a non-pharmacological, cost-effective intervention easily implementable within existing enhanced recovery after surgery protocols, early activity intervention represents an evidence-based approach suitable for routine clinical adoption in colorectal cancer surgery recovery.