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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Nov 27, 2025; 17(11): 110036
Published online Nov 27, 2025. doi: 10.4240/wjgs.v17.i11.110036
Published online Nov 27, 2025. doi: 10.4240/wjgs.v17.i11.110036
Intra-biliary cleansing during secondary duodenoscopic removal of duodenal bend biliary stents: A retrospective cohort study
Hong-Lei Zhang, Cheng Zhang, Chen Qiu, Bo-Sen Zhang, An-Hua Huang, Zhao-Yan Jiang, Liang Zheng, Hai Hu, Yu-Long Yang, Center for Gallbladder Diseases, Shanghai East Hospital Affiliated with Tongji University and Institute of Gallbladder Diseases of Tongji University School of Medicine, Shanghai 200120, China
Jian-She Yang, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai 200092, China
Co-corresponding authors: Hai Hu and Yu-Long Yang.
Author contributions: Zhang HL wrote the first draft of the manuscript; Zhang HL and Zhang C performed conceptualization and methodology, wrote the manuscript, and reviewed the literature; Qiu C and Zhang BS collected the data and performed the experiments; Yang JS and Zheng L conducted data organization and analysis; Huang AH, Yang JS, and Jiang ZY carried out the technical editing of integrating pictures, making tables and critically reviewing the research plan and manuscript; Yang YL and Hu H were responsible for the concepts, methods, research guidance, and paper revision; Zhang HL, Zhang C, Qiu C, Zhang BS, Huang AH, Yang JS, Jiang ZY, Zheng L, Hu H, and Yang YL contributed to the study conception and design, and commented on previous versions of the manuscript; and all authors read and approved the final manuscript.
Supported by the Key Specialty Construction Project of Shanghai Pudong New Area Health Commission, No. PWZzk2022-17; the Featured Clinical Discipline Project of Shanghai Pudong, No. PWYts2021-06; Clinical Research Project of Shanghai East Hospital, No. DFLC2022019; and Shanghai Dongfang Hospital Key Discipline Department of Gallstone Disease, No. 2024-DFZD-005DS.
Institutional review board statement: This study was approved by the Medical Ethics Committee of East Hospital Affiliated to Tongji University, approval No.[2022] Research Review (107).
Informed consent statement: Signed informed consent was obtained from all participants prior to the study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yu-Long Yang, MD, PhD, Academic Fellow, Chief Physician, Full Professor, Center for Gallbladder Diseases, Shanghai East Hospital Affiliated with Tongji University and Institute of Gallbladder Diseases of Tongji University School of Medicine, No. 150 Jimo Road, Shanghai 200120, China. yyl516@tongji.edu.cn
Received: May 28, 2025
Revised: July 21, 2025
Accepted: September 9, 2025
Published online: November 27, 2025
Processing time: 181 Days and 2.8 Hours
Revised: July 21, 2025
Accepted: September 9, 2025
Published online: November 27, 2025
Processing time: 181 Days and 2.8 Hours
Core Tip
Core Tip: In clinical practice, compared to single-pigtail biliary stents, patients with duodenal bend biliary stent have a significantly increased risk of chyme reflux into the bile duct and common bile duct stones (residual or recurrent). Performing intra-biliary cleansing after stent removal can improve patient prognosis. The finding of this study will increase endoscopists’ awareness of the importance of intra-biliary cleansing during biliary stent placement and replacement, thereby optimising clinical practice and improving patient prognosis.