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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Nov 27, 2025; 17(11): 109361
Published online Nov 27, 2025. doi: 10.4240/wjgs.v17.i11.109361
Published online Nov 27, 2025. doi: 10.4240/wjgs.v17.i11.109361
Quantitative evaluation for preoperative clinical stage of colorectal cancer using dynamic contrast-enhanced magnetic resonance imaging
Li-Hong Guo, Wei Qin, Xin-Hua Ou-Yang, Ye-Xing Wang, Department of General Surgery, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang 441003, Hubei Province, China
Co-first authors: Li-Hong Guo and Wei Qin.
Co-corresponding authors: Xin-Hua Ou-Yang and Ye-Xing Wang.
Author contributions: Guo LH and Qin W designed the research and wrote the first manuscript, they contributed equally to this article, they are the co-first authors of this manuscript; Guo LH, Qin W, Ou-Yang XH, and Wang YX contributed to conceiving the research and analyzing data; Ou-Yang XH and Wang YX contributed equally to this article, they are the co-corresponding authors of this manuscript; Guo LH and Qin W conducted the analysis and provided guidance for the research; and all authors reviewed and approved the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Xiangyang Central Hospital.
Informed consent statement: The written informed consent was waived owing to the retrospective and deidentified nature of this study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The data that support the results of this research is available on request from the corresponding author.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Ye-Xing Wang, Department of General Surgery, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, No. 7 Zhongyuan Road, Xiangyang 441003, Hubei Province, China. wangyexing1987@126.com
Received: July 1, 2025
Revised: August 26, 2025
Accepted: October 11, 2025
Published online: November 27, 2025
Processing time: 146 Days and 19.7 Hours
Revised: August 26, 2025
Accepted: October 11, 2025
Published online: November 27, 2025
Processing time: 146 Days and 19.7 Hours
Core Tip
Core Tip: Patients with colorectal cancer exhibited higher values of quantitative parameters [volume transfer constant (Ktrans), rate constant (Kep) and extravascular extracellular volume fraction (Ve)] of dynamic contrast-enhanced magnetic resonance imaging than those with benign tumor. Increased values of Ktrans, Kep, and Ve were correlated with more advanced primary tumor and lymph node stages. The values of Ktrans, Kep and Ve exhibited good performance in diagnosing colorectal cancer and preoperative assessment of clinical stages.