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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Oct 27, 2025; 17(10): 111943
Published online Oct 27, 2025. doi: 10.4240/wjgs.v17.i10.111943
Published online Oct 27, 2025. doi: 10.4240/wjgs.v17.i10.111943
Unusually rapid growth of a duodenal muco-submucosal elongated polyp: A case report
Yi Yang, Ding-Fu Zhong, Department of Gastroenterology, Affiliated Jinhua Hospital of Wenzhou Medical University, Jinhua People's Hospital, Jinhua 321000, Zhejiang Province, China
Author contributions: Yang Y helped write and edit the manuscript and collect data; Zhong DF helped write the paper; all the authors have read and approved the content of the manuscript.
Informed consent statement: Written informed consent was obtained from the patient.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yi Yang, MD, Department of Gastroenterology, Affiliated Jinhua Hospital of Wenzhou Medical University, Jinhua People's Hospital, No. 267 Danxi East Road, Jindong District, Jinhua 321000, Zhejiang Province, China. yangyi_0325@163.com
Received: July 21, 2025
Revised: August 4, 2025
Accepted: September 3, 2025
Published online: October 27, 2025
Processing time: 97 Days and 11.6 Hours
Revised: August 4, 2025
Accepted: September 3, 2025
Published online: October 27, 2025
Processing time: 97 Days and 11.6 Hours
Core Tip
Core Tip: Muco-submucosal elongated polyps (MSEPs) are rare benign gastrointestinal lesions, typically found in the colon and infrequently in the small intestine. We report a case of a rapidly enlarging MSEP in the duodenum, which expanded from a 1.5-cm mucosal elevation to a 10-cm pedunculated lesion within 15 months. Complete en bloc resection was achieved by endoscopic submucosal dissection, and histology confirmed the diagnosis. This case highlights the potential for rapid growth of duodenal MSEPs and emphasizes the importance of regular endoscopic surveillance, even in patients without symptoms.