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Retrospective Cohort Study
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World J Gastrointest Surg. Oct 27, 2025; 17(10): 109729
Published online Oct 27, 2025. doi: 10.4240/wjgs.v17.i10.109729
Application of total thoracoscopic ultrasonic scalpel resection in esophageal cancer patients
Tian-Yi Zhang, Ming-Zhi Ren, Xiao-Kang Gong, Jun Ma
Tian-Yi Zhang, Ming-Zhi Ren, Xiao-Kang Gong, Jun Ma, Department of Thoracic Surgery, Tangdu Hospital, The Second Affiliated Hospital of Air Force Medical University, Xi’an 710038, Shaanxi Province, China
Author contributions: Zhang TY and Ma J contributed to design of the study, data acquisition and analysis, and manuscript draft; Ren MZ and Gong XK assisted with data collection; Ma J supervised and coordinated the project. All authors approved the final version manuscript.
Institutional review board statement: This study was approved by the Ethics Committee of Tangdu Hospital, The Second Affiliated Hospital of Air Force Medical University, No. K-HG-202505-11.
Informed consent statement: The data used in this study did not involve identifiable patient information, thus, the requirement for informed consent was waived by the Ethics Committee of Tangdu Hospital, The Second Affiliated Hospital of Air Force Medical University. All patient data were obtained, recorded, and managed exclusively for this study, with strict confidentiality maintained, ensuring no harm to the patients.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jun Ma, MD, Department of Thoracic Surgery, Tangdu Hospital, The Second Affiliated Hospital of Air Force Medical University, No. 569 Xinsi Road, Baqiao District, Xi’an 710038, Shaanxi Province, China. majj088@126.com
Received: June 5, 2025
Revised: July 10, 2025
Accepted: August 28, 2025
Published online: October 27, 2025
Processing time: 140 Days and 17.6 Hours
Core Tip

Core Tip: Esophageal cancer remains a highly aggressive malignancy with significant implications for patient health. This retrospective cohort study demonstrates superior outcomes with total thoracoscopic ultrasonic scalpel resection vs electrosurgical resection. The ultrasonic scalpel significantly optimizes perioperative indicators, reduces postoperative pain, enhances immune function, suppresses inflammatory mediator release, preserves pulmonary function, while demonstrating a lower complication rate. These advantages support its broader clinical adoption for esophageal cancer resection.