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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Surg. Oct 27, 2025; 17(10): 108938
Published online Oct 27, 2025. doi: 10.4240/wjgs.v17.i10.108938
Published online Oct 27, 2025. doi: 10.4240/wjgs.v17.i10.108938
Minimally invasive management of acute perforated cholecystitis: The role of percutaneous transhepatic cholecystostomy
Mai Mazarieb, Department of Surgery, Royal Free Hospital, Barnet Hospital, London NW2 2QG, United Kingdom
Amjad Parvaiz, Surgical Unit, Champalimaud Clinic Center, Champalimaud Foundation, Lisbon 1400-038, Portugal
Ubaida Hawashna, Department of Surgery, Rabin Medical Center, Petach Tikva 49100, Israel
Yackov Romanenko, Eli Atar, Units of Vascular and Interventional Radiology, Department of Diagnostic Radiology, Rabin Medical Center, Hasharon and Beilinson Hospitals, Petach Tikva 49100, Israel
Gil N Bachar, Departments of Radiology (Interventional Radiology Unit), Rabin Medical Center (Beilinson Campus), Petach Tikva 49100, Israel
Co-corresponding authors: Eli Atar and Gil N Bachar.
Author contributions: Mazarieb M, Parvaiz A, Hawashna U, Romanenko Y, Atar E, and Bachar GN designed the research study and performed the research; Mazarieb M, Atar E, and Bachar GN analyzed the data, and wrote the manuscript; Atar E and Bachar GN contributed equally to this article, they are the co-corresponding authors of this manuscript; and all authors thoroughly reviewed and endorsed the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Rabin Medical Center, No. RMC-05010-24.
Informed consent statement: This study is a retrospective analysis of anonymized patient data. Therefore, in accordance with institutional guidelines and national regulations, written informed consent was not required.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The data supporting the findings of this study are not publicly available due to privacy and ethical restrictions concerning participant confidentiality.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gil N Bachar, MD, Associate Professor, Director, Head, Departments of Radiology (Interventional Radiology Unit), Rabin Medical Center (Beilinson Campus), Golda campus/KKL 7, Petach Tikva 49100, Israel. gilbah@clalit.org.il
Received: April 28, 2025
Revised: May 27, 2025
Accepted: September 1, 2025
Published online: October 27, 2025
Processing time: 181 Days and 10.5 Hours
Revised: May 27, 2025
Accepted: September 1, 2025
Published online: October 27, 2025
Processing time: 181 Days and 10.5 Hours
Core Tip
Core Tip: Percutaneous transhepatic cholecystostomy (PTC) offers a safe, minimally invasive first‐line strategy for acute perforated cholecystitis in patients at high surgical risk. In our retrospective cohort of 30 acute perforated cholecystitis cases, PTC achieved clinical stabilization in 61.4% of non‐operated patients, facilitated elective cholecystectomy in half the cohort, and was associated with low, manageable complication rates. Over a 24-month follow-up, most patients managed with PTC alone maintained durable health improvements, underscoring its potential both as a bridge to surgery and as definitive treatment in select critically ill populations.