Fu Q, Xiang HF, Zhang SY, Liu XL, Yu JH, Zhang ZQ. Short-term weight control and complications in patients with obesity following laparoscopic sleeve gastrectomy. World J Gastrointest Surg 2026; 18(4): 116480 [DOI: 10.4240/wjgs.v18.i4.116480]
Corresponding Author of This Article
Zhen-Qi Zhang, BM, Residency, Department of Anesthesiology, The Third People’s Hospital of Chengdu, No. 19 Yangshi Street, Qingyang District, Chengdu 610000, Sichuan Province, China. michellezzq29@163.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Apr 27, 2026 (publication date) through Apr 24, 2026
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Journal Information of This Article
Publication Name
World Journal of Gastrointestinal Surgery
ISSN
1948-9366
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Fu Q, Xiang HF, Zhang SY, Liu XL, Yu JH, Zhang ZQ. Short-term weight control and complications in patients with obesity following laparoscopic sleeve gastrectomy. World J Gastrointest Surg 2026; 18(4): 116480 [DOI: 10.4240/wjgs.v18.i4.116480]
Qiang Fu, Hui-Fen Xiang, Si-Yu Zhang, Xiao-Lan Liu, Zhen-Qi Zhang, Department of Anesthesiology, The Third People’s Hospital of Chengdu, Chengdu 610000, Sichuan Province, China
Jia-Hui Yu, Department of Gastrointestinal and Minimally Invasive Surgery Center, The Third People’s Hospital of Chengdu, Chengdu 610000, Sichuan Province, China
Author contributions: Fu Q designed and conducted the study and drafted the manuscript; Xiang HF and Zhang SY performed data analysis; Liu XL and Yu JH provided clinical guidance and valuable inputs throughout the study; Zhang ZQ conceived and supervised the study and critically revised the manuscript; and all the authors were responsible for the decision to submit the manuscript for publication.
Institutional review board statement: This study was approved by the Medical Ethics Committee of The Third People’s Hospital of Chengdu, approval No. 2024-S-252.
Informed consent statement: The ethics committee approved the waiver of informed consent due to the retrospective nature of this study.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: The data used in this study can be obtained from the corresponding author upon request.
Corresponding author: Zhen-Qi Zhang, BM, Residency, Department of Anesthesiology, The Third People’s Hospital of Chengdu, No. 19 Yangshi Street, Qingyang District, Chengdu 610000, Sichuan Province, China. michellezzq29@163.com
Received: December 12, 2025 Revised: January 15, 2026 Accepted: February 26, 2026 Published online: April 27, 2026 Processing time: 132 Days and 22.3 Hours
Abstract
BACKGROUND
Laparoscopic sleeve gastrectomy (LSG) is an effective bariatric procedure; however, its short-term outcomes and comorbidity resolution remain underexplored.
AIM
To evaluate short-term weight loss outcomes and comorbidity improvements in patients with obesity within 12 months after LSG.
METHODS
A single-center retrospective analysis was conducted on 122 patients with obesity who underwent LSG between June 2019 and June 2024. Weight, body mass index, excess weight loss percentage, total weight loss percentage, and metabolic parameters were assessed preoperatively and 1 month, 3 months, 6 months, and 12 months postoperatively.
RESULTS
Significant reductions in weight (115.36 ± 18.72 kg to 90.65 ± 18.59 kg) and body mass index (38.73 ± 5.17 kg/m2 to 30.32 ± 5.01 kg/m2) were observed at 12 months (P < 0.05). Excess weight loss percentage reached 71.84% and total weight loss percentage showed a consistent upward trend. Marked improvements were also observed in type 2 diabetes, hypertension, dyslipidemia, hyperuricemia, and fatty liver disease (all P < 0.05).
CONCLUSION
LSG is effective for achieving significant short-term weight loss and ameliorating obesity-related metabolic comorbidities, highlighting its value as a therapeutic intervention for severe obesity.
Core Tip: In this single-center retrospective study, 122 Chinese adults with obesity underwent laparoscopic sleeve gastrectomy and were followed up for 12 months. Mean body mass index fell from 38.7 kg/m2 to 30.3 kg/m2, excess weight loss reached 71.8%, and 72% of patients achieved effective weight loss. Among 28 patients with type 2 diabetes, 54% achieved complete remission; significant reductions were also observed in hypertension, hyperuricemia, and fatty liver. No major surgical complications were observed. These results confirm that laparoscopic sleeve gastrectomy produces rapid, sustained weight loss and broad metabolic benefits within the first postoperative year.
