Zhou JW, Jin CF, Lei WS, Zhu ML, Yu XP, Yu WH. Appendiceal bleeding caused by angiodysplasia: A case report and review of literature. World J Gastrointest Surg 2026; 18(4): 116138 [DOI: 10.4240/wjgs.v18.i4.116138]
Corresponding Author of This Article
Wei-Hua Yu, MD, Department of Gastroenterology, The Fourth Affiliated Hospital of School of Medicine, International School of Medicine, International Institutes of Medicine, Zhejiang University, N1 Shangcheng Road, Yiwu 322000, Zhejiang Province, China. yuweihua84@zju.edu.cn
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
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This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Apr 27, 2026 (publication date) through Apr 24, 2026
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Journal Information of This Article
Publication Name
World Journal of Gastrointestinal Surgery
ISSN
1948-9366
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Zhou JW, Jin CF, Lei WS, Zhu ML, Yu XP, Yu WH. Appendiceal bleeding caused by angiodysplasia: A case report and review of literature. World J Gastrointest Surg 2026; 18(4): 116138 [DOI: 10.4240/wjgs.v18.i4.116138]
Jiang-Wei Zhou, Cheng-Feng Jin, Wei-Shang Lei, Wei-Hua Yu, Department of Gastroenterology, The Fourth Affiliated Hospital of School of Medicine, International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu 322000, Zhejiang Province, China
Meng-Lu Zhu, Department of Pharmacy, The Fourth Affiliated Hospital of School of Medicine, International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu 322000, Zhejiang Province, China
Xi-Ping Yu, Department of Pathology, The Fourth Affiliated Hospital of School of Medicine, International School of Medicine, International Institutes of Medicine, Zhejiang University, Yiwu 322000, Zhejiang Province, China
Author contributions: Zhou JW conceptualized the study and wrote the original draft; Zhou JW, Jin CF, and Zhu ML performed the investigation; Zhou JW, Jin CF, Lei WS, Zhu ML, Yu XP, and Yu WH reviewed, edited the draft, and carried out data curation; Yu WH supervised the study; all of the authors read and approved the final version of the manuscript to be published.
Supported by Scientific Research Fund of Zhejiang Provincial Education Department, No. Y202352681.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Wei-Hua Yu, MD, Department of Gastroenterology, The Fourth Affiliated Hospital of School of Medicine, International School of Medicine, International Institutes of Medicine, Zhejiang University, N1 Shangcheng Road, Yiwu 322000, Zhejiang Province, China. yuweihua84@zju.edu.cn
Received: November 4, 2025 Revised: November 23, 2025 Accepted: February 4, 2026 Published online: April 27, 2026 Processing time: 171 Days and 19.3 Hours
Abstract
BACKGROUND
Lower gastrointestinal bleeding is a common clinical presentation. However, appendiceal bleeding is exceedingly rare and often results in diagnostic delay or misdiagnosis.
CASE SUMMARY
We report the case of a 28-year-old man presenting with a two-day history of intermittent hematochezia. A colonoscopy revealed continuous fresh blood exuding from the appendiceal orifice. Computed tomography angiography demonstrated active bleeding from the appendix. An immediate laparoscopic appendectomy was performed. Pathological examination indicated that the bleeding originated from vascular dysplasia of the appendix. Postoperatively, no recurrence of bleeding or complications occurred, and the patient was discharged home on postoperative day 3.
CONCLUSION
Appendiceal bleeding is rare. Its cause remains obscure, challenging diagnosis. Colonoscopy is the primary diagnostic tool; appendectomy provides definitive treatment.
Core Tip: Appendiceal bleeding is extremely rare. We reported a case of a young man with hematochezia diagnosed with appendiceal bleeding via colonoscopy and computed tomography angiography. Laparoscopic appendectomy confirmed vascular malformation as the cause. Through literature review, we summarized clinical manifestations, causes, and treatment options, aiming to provide references for clinicians. Endoscopic hemostasis is feasible but carries a risk of appendicitis. Appendectomy is considered the definitive and reliable treatment, especially after failure of conservative treatment or endoscopic management, as it prevents recurrence.
