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©Author(s) (or their employer(s)) 2026. No commercial re-use. See Permissions. Published by Baishideng Publishing Group Inc.
World J Gastrointest Surg. Feb 27, 2026; 18(2): 113867
Published online Feb 27, 2026. doi: 10.4240/wjgs.v18.i2.113867
Emergency surgery for malignant large bowel obstruction: Assessing management options and outcomes
Terence N Moyana
Terence N Moyana, Division of Diagnostic and Molecular Pathology, The Ottawa Hospital and University of Ottawa, Ottawa K1H 8L6, Ontario, Canada
Author contributions: Moyana TN is responsible for all aspects of the work, including the conception, design, research, writing, and finalization of the manuscript.
Conflict-of-interest statement: The author reports no relevant conflicts of interest for this article.
Corresponding author: Terence N Moyana, MD, FRCPC, FCAP, Full Professor, Division of Diagnostic and Molecular Pathology, The Ottawa Hospital and University of Ottawa, 501 Smyth Road, Ottawa K1H 8L6, Ontario, Canada. tmoyana@toh.ca
Received: September 5, 2025
Revised: November 11, 2025
Accepted: December 3, 2025
Published online: February 27, 2026
Processing time: 174 Days and 14.1 Hours
Abstract

Malignant large bowel obstruction accounts for a disproportionately high percentage of colorectal cancer emergencies. Traditionally, it was treated by emergency surgery, which, depending on the circumstances, could involve primary resection or staged procedures. However, this was associated with considerable morbidity and mortality. Qiu et al sought to improve this by creating a nomogram that can be used as a benchmark in the management of such patients. Although the nomogram is meant to be a predictive model for recurrence, it is only based on a snapshot of parameters at 2 years. To be of maximum benefit to patients consenting for surgery and their caregivers, the performance of the model should be assessed over both the short- and long-term intervals (e.g., 30, 60, and 90 days as well as 1, 2, and 5 years or longer). Moreover, the heterogeneity of colorectal cancer (e.g., right-sided vs left-sided cancers vs rectal cancers) limits the nomogram’s applicability in certain situations, as it was constructed using a one-size-fits-all approach. It is also noteworthy that the increasing acceptance of self-expanding metal stents as an option to emergency surgery provides significant benefits for patients with malignant large bowel obstruction. Lastly, it is important to distinguish residual disease from recurrence, as conflating the two may confound parameters and study endpoints. This distinction has gained renewed interest with recent advances in liquid biopsies and genomics and how they can better define minimal residual disease.

Keywords: Malignant large bowel obstruction; Emergency surgery; Disease recurrence; Self-expanding metal stents; Bridge-to-surgery; Right vs left colon cancer; Molecular biomarkers

Core Tip: Malignant large bowel obstruction was traditionally managed by emergency surgery, a strategy associated with considerable morbidity and mortality. The introduction of self-expanding metal stents in the 1990s provided an option to emergency surgery with significant benefits for these patients. Looking ahead, advances in liquid biopsies and molecular biomarkers are poised to enhance cancer diagnostics and the monitoring of minimal residual disease, promising improved outcomes in the future.