One-anastomosis gastric bypass vs sleeve gastrectomy for complications, perioperative status, and quality of life: Meta-analysis

doi:10.4240/wjgs.v18.i1.112017

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 18, Issue 1

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (57)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-8) series, Tables (1-6) series.

Item

Count

PDF

HTML

Figures (1-8)

Tables (1-6)

Sum=36

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

Download

Sum=24

Jan 27, 2026 (publication date) through Jan 28, 2026

Times Cited of This Article

Times Cited (0)

Journal Information of This Article

Publication Name

World Journal of Gastrointestinal Surgery

ISSN

1948-9366

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Meta-Analysis

World J Gastrointest Surg. Jan 27, 2026; 18(1): 112017
Published online Jan 27, 2026. doi: 10.4240/wjgs.v18.i1.112017

One-anastomosis gastric bypass vs sleeve gastrectomy for complications, perioperative status, and quality of life: Meta-analysis

Hyder Osman Mirghani

Hyder Osman Mirghani, Department of Internal Medicine, University of Tabuk, Tabuk 51941, Saudi Arabia

Author contributions: Mirghani HO performed the conception and design of the study, the literature search, the drafting, and critical revision, and provided the final approval of the version to be published.

Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.

PRISMA 2009 Checklist statement: The authors have read the PRISMA 2009 Checklist, and the manuscript was prepared and revised according to the PRISMA 2009 Checklist.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Hyder Osman Mirghani, MD, Full Professor, Department of Internal Medicine, University of Tabuk, Prince Fahd Bin Sultan Street, Tabuk 51941, Saudi Arabia. s.hyder63@hotmail.com

Received: July 16, 2025
Revised: August 20, 2025
Accepted: November 14, 2025
Published online: January 27, 2026
Processing time: 190 Days and 2.4 Hours

Abstract

BACKGROUND

One-anastomosis gastric bypass (OAGB) and sleeve gastrectomy (SG) are safe and effective bariatric surgeries. Literature assessing the complications, mortality, operative time/minutes, hospital stay/days, gastroesophageal reflux (GORD), malnutrition, and quality of life is scarce.

AIM

To compare OAGB and SG regarding the above outcomes.

METHODS

We searched 4 databases from inception up to July 2025. The keywords bariatric surgery, metabolic surgery, gastric bypass, SG, complications, perioperative, quality of life, operative time, hospital stay, GORD, malnutrition, and mortality were used. Out of 1163 studies retrieved, 54 full texts were reviewed, and 31 studies were included in the meta-analysis.

RESULTS

No significant differences were evident between OAGB and SG regarding complications, odds ratio (OR), 1.37, 95% confidence interval (CI): 0.78-2.41. Operative time/minutes, hospital stay/days, and quality of life were similar between the two procedures, mean differences, 2.55, 95%CI: 3.61-8.70; -0.55, 95%CI: -1.12 to 0.02; and -0.37, 95%CI: -1.18 to 0.43 respectively, in sub-analyses including super-obesity and high diabetes, no significant differences were found regarding complications rate and operative time with higher hospital stay in patients with diabetes. Mortality and GORD were higher in SG, OR, 4.70, 95%CI: 1.64-13.52, and OR, 3.23, 95%CI: 1.56-6.72, while malnutrition was more common in OAGB, OR, 0.46, 95%CI: 0.36-0.59.

CONCLUSION

There were no differences between OAGB and SG regarding complications, mortality, operation time/minutes, hospital stay/days, and quality of life. Mortality and GORD were higher in SG, while malnutrition was higher in OAGB. Further well-controlled trials comparing OAGB and SG regarding long-term outcomes are needed.

Keywords: One anastomosis gastric bypass; Sleeve gastrectomy; Complications; Quality of life; Operative time; Mortality; Hospital stay

Core Tip: One-anastomosis gastric bypass and sleeve gastrectomy are the most commonly performed bariatric surgeries; both are safe and effective for weight reduction and diabetes remission. However, the choice between the two operations is to be determined. In this meta-analysis, we compared the two operations in terms of the complication rate, mortality, operative time/minutes, hospital stay/days, gastroesophageal reflux, nutritional deficiencies, and quality of life. This study gave a broad insight to inform the scientific community and help the surgeon to choose the best intervention for patients with obesity and diabetes.