Liu LH, Wu SB, Zhou LY, Cai LL, Cao CP, Huang Y. Effect of early stepwise nutrition management on feeding tolerance of postoperative patients with gastric cancer. World J Gastrointest Surg 2025; 17(12): 111864 [DOI: 10.4240/wjgs.v17.i12.111864]
Corresponding Author of This Article
Yao Huang, Supervising Nurse, Department of Gastrointestinal Surgery and Hospital, Jiujiang University Affiliated Hospital, No. 57 Xunyang East Road, Xunyang District, Jiujiang 332000, Jiangxi Province, China. 294869394@qq.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Dec 27, 2025 (publication date) through Dec 25, 2025
Times Cited of This Article
Times Cited (0)
Journal Information of This Article
Publication Name
World Journal of Gastrointestinal Surgery
ISSN
1948-9366
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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Liu LH, Wu SB, Zhou LY, Cai LL, Cao CP, Huang Y. Effect of early stepwise nutrition management on feeding tolerance of postoperative patients with gastric cancer. World J Gastrointest Surg 2025; 17(12): 111864 [DOI: 10.4240/wjgs.v17.i12.111864]
Li-Hua Liu, Su-Bing Wu, Le-Yi Zhou, Li-Li Cai, Chuan-Pei Cao, Yao Huang, Department of Gastrointestinal Surgery and Hospital, Jiujiang University Affiliated Hospital, Jiujiang 332000, Jiangxi Province, China
Author contributions: Liu LH designed the study, analyzed data, and drafted the manuscript; Wu SB, Zhou LY, Cai LL, and Cao CP contributed to data collection and manuscript revision; Huang Y supervised the study design, reviewed the manuscript critically for intellectual content, and finalized the submission; all authors have read and approved the final manuscript.
Institutional review board statement: This study was reviewed and approved by the Institutional Review Board of Jiujiang University Affiliated Hospital.
Informed consent statement: All study participants and their legal guardians provided written informed consent prior to study enrolment.
Conflict-of-interest statement: The authors report no relevant conflicts of interest.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yao Huang, Supervising Nurse, Department of Gastrointestinal Surgery and Hospital, Jiujiang University Affiliated Hospital, No. 57 Xunyang East Road, Xunyang District, Jiujiang 332000, Jiangxi Province, China. 294869394@qq.com
Received: August 15, 2025 Revised: September 14, 2025 Accepted: November 10, 2025 Published online: December 27, 2025 Processing time: 131 Days and 18.2 Hours
Abstract
BACKGROUND
Postoperative nutritional management of gastric cancer (GC) remains a problem that needs to be solved in clinical treatment.
AIM
To develop an early graded nutrition management plan and evaluate its impact on feeding tolerance, nutritional status, and prognosis.
METHODS
In total, 142 patients who underwent laparoscopic radical gastrectomy at Jiujiang University Affiliated Hospital between August 2021 and August 2022 were included in this study. Based on postoperative nutritional management and feeding, the patients were divided into observation and control groups. The general information questionnaire, Visual Analog Scale, and Pittsburgh Sleep Quality Index were used to evaluate pain and sleep of patients, respectively. Independent sample t-test and χ2 test were used to analyze differences between groups.
RESULTS
The feeding intolerance rates in the control and observation groups were 13.2% and 4.1%, respectively. Hospitalization time and first defecation times in the observation group were shorter than those in the control group. Hemoglobin, prealbumin, transferrin, and immunological indices in the observation group were significantly higher than those in the control group 7 days after surgery, whereas calcitonin levels were significantly lower than those in the control group (P < 0.05). In general, the nutritional status of the observation group was better than that of the control group, and pain and sleep quality scores improved.
CONCLUSION
Compared with the conventional postoperative feeding, early stepwise nutritional management can significantly enhance the nutritional status of patients with GC after surgery, improve their feeding tolerance, and reduce postoperative complications.
Core Tip: Early stepwise nutrition management benefits postoperative gastric cancer patients. It reduces feeding intolerance, shortens hospitalization and first defecation time, improves nutritional and immunological status, and enhances pain and sleep quality, with no significant impact on overall survival.
