Improving metabolic and inflammatory balance prevents periodontal complications in diabetes

doi:10.4239/wjd.v17.i1.115685

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Jan 15, 2026 (publication date) through Jan 14, 2026

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World Journal of Diabetes

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1948-9358

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Letter to the Editor

World J Diabetes. Jan 15, 2026; 17(1): 115685
Published online Jan 15, 2026. doi: 10.4239/wjd.v17.i1.115685

Improving metabolic and inflammatory balance prevents periodontal complications in diabetes

Hong-Wei Tang, Nan Zhang

Hong-Wei Tang, Department of Endocrinology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China

Hong-Wei Tang, Nan Zhang, Department of Hematology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China

Author contributions: Tang HW drafted the manuscript and conducted the literature review; Zhang N conceived the topic, supervised the overall work, and critically revised the manuscript for important intellectual content; both authors approved the final version of the manuscript.

Conflict-of-interest statement: The authors declare that there are no conflicts of interest related to this work.

Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Nan Zhang, MD, PhD, Department of Hematology, The Second Affiliated Hospital of Chongqing Medical University, No. 288 Tianwen Avenue, Nan’an District, Chongqing 400010, China. zhangnan@hospital.cqmu.edu.cn

Received: October 22, 2025
Revised: November 12, 2025
Accepted: November 28, 2025
Published online: January 15, 2026
Processing time: 83 Days and 22.6 Hours

Core Tip

Core Tip: Periodontitis is a frequent but often overlooked complication of type 2 diabetes, arising from chronic metabolic and inflammatory imbalance. Real-world evidence suggests that improving metabolic and inflammatory regulation may reduce periodontal complications and support overall health. Recognizing oral health as an essential part of comprehensive diabetes care highlights the importance of interdisciplinary collaboration between endocrinology and dentistry for better patient outcomes.