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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Oct 15, 2025; 16(10): 110041
Published online Oct 15, 2025. doi: 10.4239/wjd.v16.i10.110041
Published online Oct 15, 2025. doi: 10.4239/wjd.v16.i10.110041
Anti-inflammatory effects of cannabidiol in the treatment of type 1 diabetes: A mini review
Victor Augusto Ramos Fernandes, Department of Health, Jundiaí College of Physical Education, Jundiaí 13202-550, São Paulo, Brazil
Letícia Ranucci Mendes, Department of Psychology, Centro Universitário Nossa Senhora do Patrocínio, Itu 13300-200, São Paulo, Brazil
Raphael Oliveira Ramos Franco Netto, Americana Health Department, Family Health Strategy Physician - Mais Médicos Program, Americana 13465-050, São Paulo, Brazil
Felipe Lovaglio Belozo, Department of Physical Education, State University of Campinas, Campinas 13083-970, São Paulo, Brazil
André Alves Bezerra, Department of Morphology, Faculty of Medicine of Jundiaí, Jundiai 13202-550, São Paulo, Brazil
André Alves Bezerra, Department of Radiology, Centro Universitário Nossa Senhora do Patrocínio, Itu 13300-200, São Paulo, Brazil
Camila Pascoal Correia dos Santos, Paola Tatiana Espinosa Cruel, Rogério Leone Buchaim, Department of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, São Paulo, Brazil
Daniela Vieira Buchaim, Department of Anatomy, Medical School, University Center of Ada
Marcelo Rodrigues da Cunha, Postgraduate Program in Health Sciences, Faculty of Medicine of Jundiaí, Jundiaí 13202-550, São Paulo, Brazil
Author contributions: Ramos Fernandes VA, Mendes LR, dos Santos CPC, and da Cunha MR contributed to the conceptualization of the study; Ramos Fernandes VA, Buchaim DV, and da Cunha MR contributed to the methodology; Fernandes VAR, da Cunha MR, Mendes LR, and Santos CPC contributed to the original draft preparation; Franco Netto ROR and Bezerra AA contributed to the investigation and data curation; Belozo FL, Cruel PTE, Buchaim DV, Buchaim RL, and da Cunha MR contributed to reviewing and editing the manuscript; Buchaim DV and da Cunha MR contributed to the validation; Belozo FL contributed to the research; Buchaim RL and da Cunha MR contributed to the supervision and project administration; da Cunha MR contributed to the formal analyses; All authors read and approved the final version of the manuscript.
Conflict-of-interest statement: The authors have no conflicts of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Marcelo Rodrigues da Cunha, PhD, Postgraduate Program in Health Sciences, Faculty of Medicine of Jundiaí, R. Francisco Teles 250, Jundiaí 13202-550, São Paulo, Brazil. marcelocunha@g.fmj.br
Received: May 28, 2025
Revised: June 20, 2025
Accepted: September 15, 2025
Published online: October 15, 2025
Processing time: 140 Days and 15.2 Hours
Revised: June 20, 2025
Accepted: September 15, 2025
Published online: October 15, 2025
Processing time: 140 Days and 15.2 Hours
Core Tip
Core Tip: This review discusses the potential role of cannabidiol (CBD) in modulating inflammation in type 1 diabetes (T1D). By influencing immune pathways and attenua