Copyright
©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Oct 15, 2025; 16(10): 109080
Published online Oct 15, 2025. doi: 10.4239/wjd.v16.i10.109080
Published online Oct 15, 2025. doi: 10.4239/wjd.v16.i10.109080
Type 2 diabetes complicated by dry eye syndrome: Analysis of dry eye symptoms, corneal neuropathy, and influencing factors
Wen-Tao Han, Jin Zhao, Wan-Lu Feng, Wen-Ting Ma, Department of Ophthalmology, Xianyang First People's Hospital, Xianyang 712000, Shaanxi Province, China
Co-first authors: Wen-Tao Han and Wan-Lu Feng.
Author contributions: Han WT and Feng WL contribute equally to this study as co-first authors; Han WT and Zhao J designed the study, collected and analyzed data, and wrote the manuscript; Han WT, Zhao J and Feng WL participated in the study’s conception and data collection; Han WT, Zhao J and Ma WT participated in study design and provided guidance; all authors read and approved the final version.
Institutional review board statement: This study was approved by the Ethic Committee of Xianyang First People's Hospital.
Informed consent statement: Patients were not required to give informed consent to the study because the analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written consent.
Conflict-of-interest statement: We have no financial relationships to disclose.
Data sharing statement: No additional data are available.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Wen-Ting Ma, Department of Ophthalmology, Xianyang First People's Hospital, No. 10 Biyuan Road, Qindu District, Xianyang 712000, Shaanxi Province, China.
Received: June 24, 2025
Revised: August 4, 2025
Accepted: September 16, 2025
Published online: October 15, 2025
Processing time: 113 Days and 2 Hours
Revised: August 4, 2025
Accepted: September 16, 2025
Published online: October 15, 2025
Processing time: 113 Days and 2 Hours
Core Tip
Core Tip: Patients with diabetes are more likely to have dry eyes, experience a burning sensation and foreign body sensation, exhibit corneal epithelial changes, and have a significantly higher incidence of dry eye than those without diabetes. In this study, dry eye and corneal neuropathy symptoms were observed in patients with both dry eye and type 2 diabetes, and the correlation between the two was analyzed. This study also actively explored and summarized relevant factors influencing the occurrence of dry eye in patients with diabetes to provide effective preventive treatment and improve patients’ quality of life.