Advances in the treatment of diabetic peripheral neuropathy by modulating gut microbiota with traditional Chinese medicine

doi:10.4239/wjd.v15.i8.1712

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Aug 15, 2024 (publication date) through Nov 25, 2024

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World Journal of Diabetes

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World J Diabetes. Aug 15, 2024; 15(8): 1712-1716
Published online Aug 15, 2024. doi: 10.4239/wjd.v15.i8.1712

Advances in the treatment of diabetic peripheral neuropathy by modulating gut microbiota with traditional Chinese medicine

Ye-Yao Li, Rui-Qian Guan, Zhi-Bo Hong, Yao-Lei Wang, Li-Min Pan

Ye-Yao Li, Zhi-Bo Hong, Yao-Lei Wang, Li-Min Pan, Department of Endocrinology, The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150001, Heilongjiang Province, China

Rui-Qian Guan, Department of Tuina, The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150001, Heilongjiang Province, China

Author contributions: Li YY, Guan RQ, Hong ZB, Wang YL, and Pan LM contributed to the writing, revising and proofreading of the manuscript.

Conflict-of-interest statement: There is no conflict-of-interest.

Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https: //creativecommons.org/Licenses/by-nc/4.0/

Corresponding author: Li-Min Pan, MD, Associate Chief Physician, Department of Endocrinology, The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine, No. 411 Guogeli Avenue, Nangang District, Harbin 150001, Heilongjiang Province, China. 2621902358@qq.com

Received: April 30, 2024
Revised: June 6, 2024
Accepted: June 20, 2024
Published online: August 15, 2024
Processing time: 87 Days and 4.1 Hours

Core Tip

Core Tip: Diabetic peripheral neuropathy (DPN) is associated with gut microbiota dysbiosis. Traditional Chinese medicine (TCM) compounds such as Shenqi Dihuang Decoction, Huangkui Capsules and Qidi Tangshen Granules can reduce the clinical symptoms of diabetic nephropathy by modulating gut microbiota. In this review, the authors discusse whether TCM compounds can reduce the risk of DPN by improving gut microbiota.