Review
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Jun 15, 2024; 15(6): 1111-1121
Published online Jun 15, 2024. doi: 10.4239/wjd.v15.i6.1111
Pathological mechanism of immune disorders in diabetic kidney disease and intervention strategies
Tong Zhou, Yi-Lin Fang, Tian-Tian Tian, Gui-Xia Wang
Tong Zhou, Gui-Xia Wang, Department of Endocrinology and Metabolism, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China
Tong Zhou, Yi-Lin Fang, Key Laboratory of Organ Regeneration and Transplantation of the Ministry of Education, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China
Tong Zhou, Yi-Lin Fang, National-Local Joint Engineering Laboratory of Animal Models for Human Diseases, Jilin University, Changchun 130021, Jilin Province, China
Tian-Tian Tian, School of Public Health, Jilin University, Changchun 130021, Jilin Province, China
Author contributions: Wang GX designed the review; Zhou T performed the literature revision, collected the data, and wrote the manuscript; Fang YL and Tian TT reviewed, and edited the manuscript; All authors have read and approved the final manuscript.
Supported by the National Natural Science Foundation of China, No. 82100883; and the Research Project of Educational Commission of Jilin Province of China, No. JJKH20231214KJ.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: Https://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Gui-Xia Wang, PhD, Chief Physician, Professor, Department of Endocrinology and Metabolism, The First Hospital of Jilin University, No. 1 Xinmin Street, Chaoyang District, Changchun 130021, Jilin Province, China. gwang168@jlu.edu.cn
Received: January 25, 2024
Revised: February 29, 2024
Accepted: April 15, 2024
Published online: June 15, 2024
Processing time: 138 Days and 9.7 Hours
Core Tip

Core Tip: Diabetic kidney disease (DKD) is a complex immune disease, whose occurrence and development are related to immune inflammatory factors. Currently, the immune process of DKD is mainly regulated by immune cells, inflammatory bodies, immunoglobulins, and complements; thus, interrupting its related regulatory pathways is of great clinical significance.