Published online Mar 15, 2025. doi: 10.4239/wjd.v16.i3.100592
Revised: December 18, 2024
Accepted: December 27, 2024
Published online: March 15, 2025
Processing time: 153 Days and 19.9 Hours
Diabetes is the leading cause of chronic kidney disease (CKD) and end-stage kidney disease (ESKD) worldwide. While both haemodialysis (HD) and peritoneal dialysis (PD) are commonly used treatment options for ESKD, the choice of dialysis modality in diabetic ESKD patients remains a critical decision influenced by various patient-related, healthcare system, and socio-economic factors. This article examines the factors influencing the selection of dialysis modalities for diabetic patients, with a focus on the challenges and opportunities in low-resource settings. Key considerations include the impact of comorbidities such as peripheral arterial disease and CKD-related mineral bone disorder (MBD), as well as patient preferences, caregiver burden, and the availability of healthcare infrastructure. The article highlights the need for personalized approaches to dialysis selection, considering both clinical outcomes and quality of life. It also emphasizes the potential benefits of home dialysis, including home HD and PD, in improving patient autonomy and long-term survival. The article advocates for better government policies, increased awareness, and improved support systems to enhance the accessibility and efficacy of dialysis treatments, particularly in underserved populations. Further research comparing the outcomes of different dialysis modalities across diverse settings is essential to guide global treatment strategies for diabetic ESKD patients.
Core Tip: The choice of dialysis modality in diabetic patients with end-stage kidney disease should be individualized, considering factors such as comorbidities (e.g., peripheral arterial disease, chronic kidney disease-related mineral bone disorder), patient preferences, healthcare infrastructure, and caregiver support. In low-resource settings, promoting home dialysis options and improving access to peritoneal dialysis can enhance patient outcomes and quality of life. Healthcare policies, education, and better support systems are key to optimizing dialysis choices, particularly for diabetic populations in underserved areas.