Published online Jan 15, 2025. doi: 10.4239/wjd.v16.i1.96032
Revised: September 30, 2024
Accepted: November 19, 2024
Published online: January 15, 2025
Processing time: 218 Days and 14.3 Hours
Epidemiological surveys indicate an increasing incidence of type 2 diabetes mellitus (T2DM) among children and adolescents worldwide. Due to rapid disease progression, severe long-term cardiorenal complications, a lack of effective treatment strategies, and substantial socioeconomic burdens, it has become an urgent public health issue that requires management and resolution. Adolescent T2DM differs from adult T2DM. Despite a significant increase in our understanding of youth-onset T2DM over the past two decades, the related review and evidence-based content remain limited.
To visualize the hotspots and trends in pediatric and adolescent T2DM research and to forecast their future research themes.
This study utilized the terms “children”, “adolescents”, and “type 2 diabetes”, retrieving relevant articles published between 1983 and 2023 from three citation databases within the Web of Science Core Collection (SCI, SSCI, ESCI). Utilizing CiteSpace and VoSviewer software, we analyze and visually represent the annual output of literature, countries involved, and participating institutions. This allows us to predict trends in this research field. Our analysis encompasses co-cited authors, journal overlays, citation overlays, time-zone views, keyword analysis, and reference analysis, etc.
A total of 9210 articles were included, and the annual publication volume in this field showed a steady growth trend. The United States had the highest number of publications and the highest H-index. The United States also had the most research institutions and the strongest research capacity. The global hot journals were primarily diabetes professional journals but also included journals related to nutrition, endocrinology, and metabolism. Keyword analysis showed that research related to endothelial dysfunction, exposure risk, cardiac metabolic risk, changes in gut microbiota, the impact on comorbidities and outcomes, etc., were emerging keywords. They have maintained their popularity in this field, suggesting that these areas have garnered significant research interest in recent years.
Pediatric and adolescent T2DM is increasingly drawing global attention, with genes, behaviors, environmental factors, and multisystemic interventions potentially emerging as future research hot spots.
Core Tip: A total of 9210 articles were enrolled to explore the development of type 2 diabetes mellitus (T2DM) in children and adolescents from 1983-2023. Based on analysis of the relevant indices, this study determined the development and changes of T2DM in children and adolescents as well as the characteristics of the published papers and the author’s origin. Furthermore, we conducted a visualization analysis of keywords and co-cited references. The results showed that genes, behavior, psychology, environment, and integrated diagnosis and treatment of multiple systems may constitute significant areas of future research.