Published online Jun 15, 2024. doi: 10.4239/wjd.v15.i6.1272
Revised: March 6, 2024
Accepted: April 23, 2024
Published online: June 15, 2024
Processing time: 167 Days and 23.7 Hours
Cardiovascular disease has been the leading cause of morbidity and mortality for type 2 diabetes mellitus (T2DM) patients over the last decade.
To determine whether layer-specific global longitudinal strain (GLS) combined with peak strain dispersion (PSD) can be used to assess left ventricle (LV) myocar
We enrolled 97 T2DM patients, 70 T2DM + HP patients and 101 healthy subjects. Layer-specific GLS and PSD were calculated by EchoPAC software in apical three-, four- and two-chamber views. GLS of the epimyocardial, middle-layer and endo
There were significant differences in GLSepi, GLSmid, GLSendo, and PSD bet
Layer-specific GLS and PSD were associated with LV myocardium systolic dysfunction in T2DM patients, T2DM patients with HP. T2DM patients with HP have more severe LV myocardium systolic dysfunction than T2DM patients without HP and normal control patients. The combination of layer-specific GLS and PSD may provide additional prognostic information for T2DM patients with or without HP.
Core Tip: Left ventricle (LV) myocardium systolic dysfunction was found in type 2 diabetes mellitus (T2DM) patients, T2DM patients with hypertension (HP) by layer-specific global longitudinal strain (GLS) and peak strain dispersion (PSD). T2DM patients with HP have more serious LV myocardium systolic dysfunction than T2DM patients without HP and normal control patients. Combined layer-specific GLS and PSD may provide additional prognostic information for T2DM patients with or without HP.