Observational Study
Copyright ©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Diabetes. Jun 15, 2024; 15(6): 1272-1279
Published online Jun 15, 2024. doi: 10.4239/wjd.v15.i6.1272
Subclinical impairment of left ventricular myocardium function in type 2 diabetes mellitus patients with or without hypertension
Zeng-Guang Chen, Guang-An Li, Jun Huang, Li Fan
Zeng-Guang Chen, Department of Cardiology, The Affiliated Changzhou Second People’s Hospital with Nanjing Medical University, Changzhou 213000, Jiangsu Province, China
Guang-An Li, Jun Huang, Li Fan, Department of Echocardiography, The Affiliated Changzhou Second People’s Hospital with Nanjing Medical University, Changzhou 213000, Jiangsu Province, China
Co-first authors: Zeng-Guang Chen and Guang-An Li.
Author contributions: Chen ZG, Li GA, and Huang J designed the study and carried out the study, data collection, and analysis; Chen ZG and Li GA wrote the manuscript; Huang J revised the manuscript, and collected the type 2 diabetes mellitus patients and healthy subjects; Fan L performed the statistical analysis.
Supported by the Science and Technology Project of Changzhou Health Commission, No. ZD202342.
Institutional review board statement: This research was reviewed and approved by the Human Research and Ethics Committee of the Affiliated Changzhou Second People’s Hospital of Nanjing Medical University [Approval No. (2016)YLJSE009].
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Data sharing statement: All data collected during the study are available from the Corresponding author by request: Huang J, E-mail: 305669112@qq.com.
STROBE statement: The authors have read the STROBE Statement—checklist of items, and the manuscript was prepared and revised according to the STROBE Statement—checklist of items.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Jun Huang, MD, PhD, Chief Doctor, Postdoc, Teacher, Department of Echocardiography, The Affiliated Changzhou Second People’s Hospital with Nanjing Medical University, No. 68 Gelu Road, Changzhou 213000, Jiangsu Province, China. 305669112@qq.com
Received: December 26, 2023
Revised: March 6, 2024
Accepted: April 23, 2024
Published online: June 15, 2024
Processing time: 167 Days and 23.7 Hours
Core Tip

Core Tip: Left ventricle (LV) myocardium systolic dysfunction was found in type 2 diabetes mellitus (T2DM) patients, T2DM patients with hypertension (HP) by layer-specific global longitudinal strain (GLS) and peak strain dispersion (PSD). T2DM patients with HP have more serious LV myocardium systolic dysfunction than T2DM patients without HP and normal control patients. Combined layer-specific GLS and PSD may provide additional prognostic information for T2DM patients with or without HP.