Jugnet AC, Benard T, Lequint C, Bobony E, Pieheiro AR, Winther T, Penfornis A, Dardari D. Intact fish skin graft a new hope for the treatment of diabetic foot ulcers: A case report. World J Diabetes 2024; 15(12): 2353-2359 [DOI: 10.4239/wjd.v15.i12.2353]
Corresponding Author of This Article
Dured Dardari, PhD, Academic Editor, Doctor, Department of Diabetology, Centre Hospitalier Sud Francilien, 40 Avenue Serge Dassault, Corbeil Essonne 91100, France. dured.dardari@chsf.fr
Research Domain of This Article
Endocrinology & Metabolism
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Diabetes. Dec 15, 2024; 15(12): 2353-2359 Published online Dec 15, 2024. doi: 10.4239/wjd.v15.i12.2353
Intact fish skin graft a new hope for the treatment of diabetic foot ulcers: A case report
Anne Christine Jugnet, Tatiana Benard, Corinne Lequint, Elise Bobony, Anna-Rosiana Pieheiro, Thomas Winther, Alfred Penfornis, Dured Dardari
Anne Christine Jugnet, Tatiana Benard, Corinne Lequint, Elise Bobony, Anna-Rosiana Pieheiro, Thomas Winther, Alfred Penfornis, Dured Dardari, Department of Diabetology, Centre Hospitalier Sud Francilien, Corbeil Essonne 91100, France
Author contributions: Dardari D and Penfornis A designed research; Dardari D and Jugnet AC performed research; Benard T, Lequint C, Bobony E, Pieheiro AR, Dardari D contributed new reagents or analytic tools; Dardari D wrot the paper. All authors have read and agreed to the published version of the manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Dured Dardari, PhD, Academic Editor, Doctor, Department of Diabetology, Centre Hospitalier Sud Francilien, 40 Avenue Serge Dassault, Corbeil Essonne 91100, France. dured.dardari@chsf.fr
Received: February 18, 2024 Revised: April 28, 2024 Accepted: July 19, 2024 Published online: December 15, 2024 Processing time: 273 Days and 8 Hours
Abstract
BACKGROUND
Diabetic foot ulcers (DFUs) are a real public health problem which carry a high risk of amputation. The treatment of DFUs is based on general management such as the treatment of infection, arterial disease, and offloading, but recent studies have shown that the quality of the local covering can impact the healing rate.
CASE SUMMARY
We report the case of a 39-year-old man, living with diabetes since the age of 15, who developed DFU on the dorsum of his left foot, with muscle and tendon involvement. Conventional management with intensive diabetes control, surgery, treatment of infection and negative pressure therapy gave only limited results. The patient benefited from the application of an intact fish skin graft with complete epithelialisation of the ulcer after 10 weeks of treatment.
CONCLUSION
The use of intact fish skin graft appears to be a promising option for deep DFUs.
Core Tip: Diabetic foot ulcers (DFUs) are a real public health problem which carry a high risk of amputation. The treatment of DFUs is based on general management such as the treatment of infection, arterial disease, and offloading, whereas the application of an intact fish skin graft may be a new hope for the treatment of DFU.
