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World J Diabetes. May 15, 2023; 14(5): 560-564
Published online May 15, 2023. doi: 10.4239/wjd.v14.i5.560
COVID-19 vaccination and diabetic ketoacidosis
Beuy Joob, Viroj Wiwanitkit
Beuy Joob, Academic Center, Sanitation1 Medical Academic Center, Bangkok 1033300, Thailand
Viroj Wiwanitkit, Community Medicine, DY Patil Vidhyapeeth, Pune 233230, India
Author contributions: Joob B and Wiwanitkit V contributed equally to this work; Joob B and Wiwanitkit V give the ideas; Joob B wrote and analyzed the data; Wiwanitkit V supervised; All authors have read and approve the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Beuy Joob, PhD, Adjunct Associate Professor, Academic Center, Sanitation1 Medical Academic Center, Bangkok 1033300, Thailand. beuyjoob@hotmail.com
Received: December 15, 2022
Peer-review started: December 15, 2022
First decision: January 17, 2023
Revised: February 1, 2023
Accepted: April 12, 2023
Article in press: April 12, 2023
Published online: May 15, 2023
Processing time: 151 Days and 5.2 Hours
Abstract

An efficient coronavirus disease 2019 (COVID-19) vaccine is urgently required to fight the pandemic due to its high transmission rate and quick dissemination. There have been numerous reports on the side effects of the COVID-19 immu-nization, with a focus on its negative effects. Clinical endocrinology is extremely interested in the endocrine issue that arises after receiving the COVID-19 vaccine. As was already mentioned, after receiving the COVID-19 vaccine, many clinical problems could occur. Additionally, there are some compelling reports on diabetes. After receiving the COVID-19 vaccine, a patient experienced hyperosmolar hyperglycemia state, a case of newly-onset type 2 diabetes. There has also been information on a potential connection between the COVID-19 vaccine and diabetic ketoacidosis. Common symptoms include thirst, polydipsia, polyuria, palpitations, a lack of appetite, and weariness. In extremely rare clinical circumstances, a COVID-19 vaccine recipient may develop diabetes complications such as hyperglycemia and ketoacidosis. In these circumstances, routine clinical care has a successful track record. It is advised to give vaccine recipients who are vulnerable to problems, such as those with type 1 diabetes as an underlying illness, extra attention.

Keywords: Diabetes; COVID-19; Vaccine; Ketoacidosis; Effect

Core Tip: There has also been information on a potential connection between the coronavirus disease 2019 (COVID-19) vaccine and diabetic ketoacidosis. Common symptoms include thirst, polydipsia, polyuria, palpitations, a lack of appetite, and weariness. In extremely rare clinical circumstances, a COVID-19 vaccine recipient may develop diabetes complications such as hyperglycemia and ketoacidosis.