Dietary factors in Helicobacter pylori-negative early gastric cancer: Risk, protection, and mechanistic insights

doi:10.4251/wjgo.v18.i3.117083

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Mar 15, 2026 (publication date) through Mar 12, 2026

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. Mar 15, 2026; 18(3): 117083
Published online Mar 15, 2026. doi: 10.4251/wjgo.v18.i3.117083

Table 1 Dietary factors and their association with Helicobacter pylori-negative early gastric cancer

Dietary component	Effect on gastric cancer risk
High salt intake	Increases risk; associated with mucosal damage and carcinogen promotion
Processed meats	Increases risk; linked to carcinogen formation
Fruits and vegetables	Protective effect; rich in antioxidants and micronutrients
Dietary fiber	Protective effect; aids in carcinogen excretion and gut health
Mediterranean diet	Protective effect; rich in anti-inflammatory foods
Western diet	Increases risk; high in processed foods, red meats, and fats
Vitamin C	Protective effect; reduces oxidative DNA damage
Vitamin D	Mixed evidence; some studies suggest protective effect

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Citation: Fan D, Li RJ, Guo CY, Jiao Y. Dietary factors in Helicobacter pylori-negative early gastric cancer: Risk, protection, and mechanistic insights. World J Gastrointest Oncol 2026; 18(3): 117083
URL: https://www.wjgnet.com/1948-5204/full/v18/i3/117083.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i3.117083