Patients with hepatocellular carcinoma achieving a complete response to sorafenib: Three case reports and review of literature

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Jan 15, 2026 (publication date) through Jan 12, 2026

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastrointest Oncol. Jan 15, 2026; 18(1): 113099
Published online Jan 15, 2026. doi: 10.4251/wjgo.v18.i1.113099

Table 1 Serological alpha-fetoprotein values at different timepoints

Timepoint¹	Case 1	Case 2	Case 3
At diagnosis	111	2508	17.3
At initiation of sorafenib treatment	7.5	2837	4.1
At first radiological appearance of a complete response	< 2.0	2.1	< 2.0
Last available measurement	3.0	< 2.0	< 2.0

¹Reference range: < 10 μg/mL.

Citation: Lučev H, Adžić G, Pleština S, Prejac J. Patients with hepatocellular carcinoma achieving a complete response to sorafenib: Three case reports and review of literature. World J Gastrointest Oncol 2026; 18(1): 113099
URL: https://www.wjgnet.com/1948-5204/full/v18/i1/113099.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i1.113099