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Contents Volume 15 Issue 2 February 15, 2023

Editorial

Challenges to addressing the unmet medical needs for immunotherapy targeting cold colorectal cancer

Keun-Yeong Jeong

World J Gastrointest Oncol 15(2):215-224. Published online Feb 15, 2023. doi: 10.4251/wjgo.v15.i2.215

Abstract (824) | Core Tip (916) | Full Article (HTML) (2704) | Figures (1-1) (700) | Tables (1-3) (567) | Full Article (PDF)-893K (314) | Audio-1163K (13) | Received: 09/28/2022 | Revised: 12/18/2022 | Accepted: 01/09/2023 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (1341) | Timeline of Article Publication (0) | Cite | (183) | (178) | (0) | (0) | (0) | (19) | (3) | (4362) | (1) | Open

Review

Role of ferroptosis in colorectal cancer

Ya-Qi Song, Xiao-Dan Yan, Yi Wang, Zhen-Zhen Wang, Xin-Li Mao, Li-Ping Ye, Shao-Wei Li

World J Gastrointest Oncol 15(2):225-239. Published online Feb 15, 2023. doi: 10.4251/wjgo.v15.i2.225

Abstract (932) | Core Tip (895) | Full Article (HTML) (5505) | Figures (1-1) (669) | Tables (1-1) (649) | Full Article (PDF)-1268K (379) | Audio-1641K (12) | Received: 09/19/2022 | Revised: 12/15/2022 | Accepted: 01/10/2023 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (1269) | Timeline of Article Publication (0) | Cite | (148) | (167) | (0) | (0) | (0) | (3) | (7244) | (18) | Open

“Cold” colorectal cancer faces a bottleneck in immunotherapy

Jia-Liang Liu, Ming Yang, Jun-Ge Bai, Zheng Liu, Xi-Shan Wang

World J Gastrointest Oncol 15(2):240-250. Published online Feb 15, 2023. doi: 10.4251/wjgo.v15.i2.240

Abstract (888) | Core Tip (914) | Full Article (HTML) (4859) | Figures (1-1) (771) | Tables (1-1) (647) | Full Article (PDF)-1111K (391) | Audio-133K (51) | Received: 09/22/2022 | Revised: 12/18/2022 | Accepted: 01/05/2023 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (135) | Timeline of Article Publication (0) | Cite | (160) | (179) | (0) | (0) | (0) | (19) | (2) | (6722) | (17) | Open

Is the combination of immunotherapy with conventional chemotherapy the key to increase the efficacy of colorectal cancer treatment?

Jonadab E Olguin, Monica G Mendoza-Rodriguez, C Angel Sanchez-Barrera, Luis I Terrazas

World J Gastrointest Oncol 15(2):251-267. Published online Feb 15, 2023. doi: 10.4251/wjgo.v15.i2.251

Abstract (886) | Core Tip (850) | Full Article (HTML) (5449) | Figures (1-3) (733) | Tables (1-1) (596) | Full Article (PDF)-2124K (495) | Audio-2439K (21) | Received: 09/24/2022 | Revised: 11/03/2022 | Accepted: 01/10/2023 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (1532) | Timeline of Article Publication (5) | Cite | (181) | (180) | (0) | (0) | (0) | (20) | (1) | (7325) | (28) | Open

Minireviews

Serum biomarkers for the differentiation of autoimmune pancreatitis from pancreatic ductal adenocarcinoma

Octavio Caba, Carmelo Diéguez-Castillo, Joaquina Martínez-Galán, Irene González-Cebrián, Cristina Jiménez-Luna

World J Gastrointest Oncol 15(2):268-275. Published online Feb 15, 2023. doi: 10.4251/wjgo.v15.i2.268

Abstract (908) | Core Tip (876) | Full Article (HTML) (2519) | Tables (1-1) (599) | Full Article (PDF)-671K (368) | Audio-850K (19) | Received: 09/20/2022 | Revised: 11/29/2022 | Accepted: 01/17/2023 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (309) | Timeline of Article Publication (1) | Cite | (169) | (172) | (0) | (0) | (0) | (21) | (1) | (3550) | (2) | Open

Evaluation of polygenic risk score for risk prediction of gastric cancer

Xiao-Yu Wang, Li-Li Wang, Lin Xu, Shu-Zhen Liang, Meng-Chao Yu, Qiu-Yue Zhang, Quan-Jiang Dong

World J Gastrointest Oncol 15(2):276-285. Published online Feb 15, 2023. doi: 10.4251/wjgo.v15.i2.276

Abstract (970) | Core Tip (1009) | Full Article (HTML) (3921) | Figures (1-1) (570) | Tables (1-2) (580) | Full Article (PDF)-821K (354) | Audio-1022K (18) | Supplementary Material-80K (184) | Received: 11/18/2022 | Revised: 01/11/2023 | Accepted: 02/02/2023 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (1363) | Timeline of Article Publication (0) | Cite | (219) | (191) | (0) | (0) | (0) | (21) | (1) | (5519) | (11) | Open

Basic Study

Cancerous inhibitor of protein phosphatase 2A enhances chemoresistance of gastric cancer cells to oxaliplatin

Yong-Xun Zhao, Li-Bin Ma, Ze Yang, Fang Wang, Hui-Ying Wang, Jia-Yao Dang

World J Gastrointest Oncol 15(2):286-302. Published online Feb 15, 2023. doi: 10.4251/wjgo.v15.i2.286

Abstract (772) | Core Tip (1070) | Article Highlights (1361) | Full Article (HTML) (2289) | Figures (1-8) (878) | Tables (1-3) (553) | Full Article (PDF)-9642K (302) | Audio-1586K (14) | Received: 09/08/2022 | Revised: 11/23/2022 | Accepted: 01/05/2023 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (1412) | Timeline of Article Publication (1) | Cite | (173) | (188) | (0) | (0) | (0) | (26) | (2) | (4073) | (3) | Open

Increased CD4/CD8 Lymphocyte ratio predicts favourable neoadjuvant treatment response in gastric cancer: A prospective pilot study

Daniel Skubleny, Andrea Lin, Saurabh Garg, Ross McLean, Michael McCall, Sunita Ghosh, Jennifer L Spratlin, Daniel Schiller, Gina Rayat

World J Gastrointest Oncol 15(2):303-317. Published online Feb 15, 2023. doi: 10.4251/wjgo.v15.i2.303

Abstract (843) | Core Tip (892) | Article Highlights (868) | Full Article (HTML) (3614) | Figures (1-3) (873) | Tables (1-2) (538) | Full Article (PDF)-4185K (352) | Audio-620K (23) | Supplementary Material-264K (190) | Received: 10/03/2022 | Revised: 11/25/2022 | Accepted: 01/12/2023 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (1376) | Timeline of Article Publication (0) | Cite | (164) | (167) | (0) | (0) | (0) | (2) | (5432) | (13) | Open

microRNA-627-5p inhibits colorectal cancer cell proliferation, migration and invasion by targeting Wnt2

Dong-Yan Zhao, Teng-Fei Yin, Xi-Zhen Sun, Yuan-Chen Zhou, Qian-Qian Wang, Ge-Yujia Zhou, Shu-Kun Yao

World J Gastrointest Oncol 15(2):318-331. Published online Feb 15, 2023. doi: 10.4251/wjgo.v15.i2.318

Abstract (792) | Core Tip (791) | Article Highlights (795) | Full Article (HTML) (2370) | Figures (1-7) (569) | Full Article (PDF)-5930K (307) | Audio-22929K (13) | Supplementary Material-357K (166) | Received: 09/22/2022 | Revised: 11/04/2022 | Accepted: 12/31/2022 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (1209) | Timeline of Article Publication (3) | Cite | (166) | (171) | (0) | (0) | (0) | (24) | (1) | (3306) | (8) | Open

Potent bromodomain and extraterminal domain inhibitor JAB-8263 suppresses MYC expression and exerts anti-tumor activity in colorectal cancer models

Xin-Mo Liu, Shao-You Xia, Wei Long, Hai-Jun Li, Gui-Qun Yang, Wen Sun, Song-Yan Li, Xiao-Hui Du

World J Gastrointest Oncol 15(2):332-342. Published online Feb 15, 2023. doi: 10.4251/wjgo.v15.i2.332

Abstract (834) | Core Tip (877) | Article Highlights (889) | Full Article (HTML) (2356) | Figures (1-4) (554) | Full Article (PDF)-6450K (331) | Audio-904K (14) | Received: 11/20/2022 | Revised: 12/21/2022 | Accepted: 12/31/2022 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (1215) | Timeline of Article Publication (0) | Cite | (179) | (170) | (0) | (0) | (0) | (18) | (1) | (3299) | (2) | Open

Retrospective Cohort Study

Prognostic value of claudin 18.2 expression in gastric adenocarcinoma

Erkan Kayikcioglu, Ramazan Oğuz Yüceer, Bulent Cetin, Kamuran Yüceer, Nermin Karahan

World J Gastrointest Oncol 15(2):343-351. Published online Feb 15, 2023. doi: 10.4251/wjgo.v15.i2.343

Abstract (1048) | Core Tip (876) | Article Highlights (913) | Full Article (HTML) (3908) | Figures (1-2) (873) | Tables (1-3) (521) | Full Article (PDF)-5521K (428) | Audio-527K (28) | Received: 10/29/2022 | Revised: 01/02/2023 | Accepted: 01/23/2023 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (31) | Timeline of Article Publication (1) | Cite | (157) | (160) | (0) | (0) | (0) | (21) | (1) | (5805) | (28) | Open

Meta-Analysis

Immune-related adverse events associated with immune checkpoint inhibitors for advanced gastric and gastroesophageal junction cancer: A meta-analysis

Wen-Guang Pei, Wen-Zheng Chen, Yu-Kang Wu, Sheng-Xing Tan, Zhi-Gang Jie

World J Gastrointest Oncol 15(2):352-367. Published online Feb 15, 2023. doi: 10.4251/wjgo.v15.i2.352

Abstract (857) | Core Tip (826) | Article Highlights (844) | Full Article (HTML) (3220) | Figures (1-4) (659) | Tables (1-3) (576) | Full Article (PDF)-3480K (327) | Audio-8093K (36) | Supplementary Material-1696K (177) | Received: 10/10/2022 | Revised: 10/23/2022 | Accepted: 11/29/2022 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (26) | Timeline of Article Publication (3) | Cite | (173) | (168) | (0) | (0) | (0) | (1) | (4829) | (5) | Open

Letter to the Editor

Comment on “Crosstalk between gut microbiota and COVID-19 impacts pancreatic cancer progression”

Jian Yang, Ying Liu, Shi Liu

World J Gastrointest Oncol 15(2):368-371. Published online Feb 15, 2023. doi: 10.4251/wjgo.v15.i2.368

Abstract (822) | Core Tip (808) | Full Article (HTML) (2447) | Full Article (PDF)-612K (270) | Audio-10889K (27) | Received: 11/19/2022 | Revised: 01/03/2023 | Accepted: 02/02/2023 | RCA | PubMed Central | PubMed | CrossRef | Google Scholar | Similar Articles (1349) | Timeline of Article Publication (0) | Cite | (151) | (163) | (0) | (0) | (0) | (23) | (1) | (2783) | Open

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