Characteristics and prognosis of primary gastric adenosquamous carcinoma: A multicenter retrospective study based on propensity score matching

doi:10.4251/wjgo.v18.i5.117580

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May 15, 2026 (publication date) through May 14, 2026

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Study

Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. May 15, 2026; 18(5): 117580
Published online May 15, 2026. doi: 10.4251/wjgo.v18.i5.117580

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Figure 1 Study protocol. GAC: Gastric adenocarcinoma; OS: Overall survival; PGASC: Primary gastric adenosquamous carcinoma; PSM: Propensity score matching.

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Figure 2 Overall survival in patients with gastric adenocarcinoma and primary gastric adenosquamous carcinoma. GAC: Gastric adenocarcinoma; PGASC: Primary gastric adenosquamous carcinoma.

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Figure 3 Overall survival between patients with and without chemotherapy in the locally advanced gastric adenocarcinoma and the locally advanced primary gastric adenosquamous carcinoma groups. A: The gastric adenocarcinoma group after propensity score matching. Patients receiving adjuvant chemotherapy (blue line, n = 52) showed significantly better survival than those without (red line, n = 10) (log-rank test, P < 0.010); B: The primary gastric adenosquamous carcinoma group after propensity score matching. No significant difference was observed between the chemotherapy (blue line, n = 33) and non-chemotherapy (red line, n = 29) subgroups (time-dependent Cox regression, P = 0.810).

Citation: Chen YW, Dong ZY, Wang XX, Cao Y, Lin JX, Chen H, Zhang HY, Xiao YB, Li GX, Li ZR, Chen L, Xia X, Zhang ZZ. Characteristics and prognosis of primary gastric adenosquamous carcinoma: A multicenter retrospective study based on propensity score matching. World J Gastrointest Oncol 2026; 18(5): 117580
URL: https://www.wjgnet.com/1948-5204/full/v18/i5/117580.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i5.117580

Chen YW, Dong ZY, Wang XX, Cao Y, Lin JX, Chen H, Zhang HY, Xiao YB, Li GX, Li ZR, Chen L, Xia X, Zhang ZZ. Characteristics and prognosis of primary gastric adenosquamous carcinoma: A multicenter retrospective study based on propensity score matching. World J Gastrointest Oncol 2026; 18(5): 117580 [DOI: 10.4251/wjgo.v18.i5.117580]

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