Severe hepatic steatosis as a protective prognostic factor in combined hepatocellular-cholangiocarcinoma: A multicenter pathological study

doi:10.4251/wjgo.v18.i5.116764

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May 15, 2026 (publication date) through May 14, 2026

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World Journal of Gastrointestinal Oncology

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1948-5204

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Copyright: ©Author(s) 2026. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution-NonCommercial (CC BY-NC 4.0) license. No commercial re-use. See permissions. Published by Baishideng Publishing Group Inc.

World J Gastrointest Oncol. May 15, 2026; 18(5): 116764
Published online May 15, 2026. doi: 10.4251/wjgo.v18.i5.116764

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Figure 1 Histopathological images of different degree of hepatic steatosis of the normal liver tissue in combined hepatocellular-cholangiocarcinoma patients (40 × magnification). A: Grade 0, negligible; B: Grade 1, negligible; C: Grade 2, severe; D: Grade 3, severe.

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Figure 2 Impact of the two-level degree of hepatic steatosis on the prognosis of combined hepatocellular-cholangiocarcinoma. ^aP < 0.05: Data with statistical significance. A: Recurrence-free survival; B: Early recurrence-free survival.

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Figure 3 Impact of the degree of hepatic steatosis on the prognosis of combined hepatocellular-cholangiocarcinoma patients without liver cirrhosis. ^aP < 0.05: Data with statistical significance. A: Recurrence-free survival; B: Early recurrence-free survival.

Citation: Wang H, Cao ZY, Xia CY, Sheng X, Zhao Y, Chen HZ, Cong WM, He MX, Dong H. Severe hepatic steatosis as a protective prognostic factor in combined hepatocellular-cholangiocarcinoma: A multicenter pathological study. World J Gastrointest Oncol 2026; 18(5): 116764
URL: https://www.wjgnet.com/1948-5204/full/v18/i5/116764.htm
DOI: https://dx.doi.org/10.4251/wjgo.v18.i5.116764

Wang H, Cao ZY, Xia CY, Sheng X, Zhao Y, Chen HZ, Cong WM, He MX, Dong H. Severe hepatic steatosis as a protective prognostic factor in combined hepatocellular-cholangiocarcinoma: A multicenter pathological study. World J Gastrointest Oncol 2026; 18(5): 116764 [DOI: 10.4251/wjgo.v18.i5.116764]

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