©The Author(s) 2016. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jan 15, 2016; 8(1): 99-104
Published online Jan 15, 2016. doi: 10.4251/wjgo.v8.i1.99
Published online Jan 15, 2016. doi: 10.4251/wjgo.v8.i1.99
Novel therapeutic agents in the treatment of metastatic colorectal cancer
Sachin Gopalkrishna Pai, Northwestern Medicine Developmental Therapeutics Institute, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL 60611, United States
Jyotsna Fuloria, Department of Hematology and Oncology, Ochsner Medical Center, New Orleans, LA 70121, United States
Jyotsna Fuloria, Ochsner Cancer Institute, New Orleans, LA 70121, United States
Author contributions: Pai SG prepared the initial draft; Pai SG and Fuloria J coordinated the revisions; Fuloria J approved the final draft.
Conflict-of-interest statement: The authors declare no conflicts of interest.
Correspondence to: Jyotsna Fuloria, MD, Director, Department of Hematology and Oncology, Ochsner Medical Center, 1514 Jefferson Highway, New Orleans, LA 70121, United States. jfuloria@ochsner.org
Telephone: +1-504-8423708 Fax: +1-504-8424533
Received: May 7, 2015
Peer-review started: October 14, 2015
First decision: October 15, 2015
Revised: October 20, 2015
Accepted: December 3, 2015
Article in press: December 4, 2015
Published online: January 15, 2016
Processing time: 260 Days and 13.7 Hours
Peer-review started: October 14, 2015
First decision: October 15, 2015
Revised: October 20, 2015
Accepted: December 3, 2015
Article in press: December 4, 2015
Published online: January 15, 2016
Processing time: 260 Days and 13.7 Hours
Core Tip
Core tip: This article reviews the novel agents in the management of metastatic colorectal cancer. The core principles and the evidence behind the use of these agents are discussed. Clinically relevant features are highlighted to help the health care provider involved in the care of metastatic colorectal cancer patients.