Topic Highlight
Copyright ©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Oct 15, 2015; 7(10): 221-232
Published online Oct 15, 2015. doi: 10.4251/wjgo.v7.i10.221
Immune cell interplay in colorectal cancer prognosis
Samuel E Norton, Kirsten A Ward-Hartstonge, Edward S Taylor, Roslyn A Kemp
Samuel E Norton, Kirsten A Ward-Hartstonge, Edward S Taylor, Roslyn A Kemp, Department of Microbiology and Immunology, University of Otago, Dunedin 9010, New Zealand
Author contributions: Norton SE and Ward-Hartstonge KA contributed equally to this work; all authors contributed to conceptualisation and wrote the paper.
Conflict-of-interest statement: No potential conflicts of interest relevant to this article exist.
Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Correspondence to: Roslyn A Kemp, PhD, Department of Microbiology and Immunology, University of Otago, PO Box 56, Dunedin 9010, New Zealand. roslyn.kemp@otago.ac.nz
Telephone: +64-3-4797708 Fax: +64-3-4798540
Received: April 28, 2015
Peer-review started: May 7, 2015
First decision: June 2, 2015
Revised: June 12, 2015
Accepted: August 25, 2015
Article in press: August 28, 2015
Published online: October 15, 2015
Processing time: 173 Days and 20.7 Hours
Core Tip

Core tip: The outcome of patients with colorectal cancer is influenced by the complex local immune system. Understanding how multiple relationships between immune cells may affect tumour growth or elimination will be key in designing new therapies to treat this disease.