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World J Gastrointest Oncol. Sep 15, 2026; 18(9): 120693
Published online Sep 15, 2026. doi: 10.4251/wjgo.120693
Published online Sep 15, 2026. doi: 10.4251/wjgo.120693
Syndrome differentiation nursing for gastrointestinal reactions and nutritional status in diabetic nephropathy with gastric cancer post-chemotherapy
Jia-Hui Ma, Yan Zhang, Department of Critical Care Medicine, Hai’an People’s Hospital (Hai’an Hospital Affiliated to Nantong University), Nantong 226600, Jiangsu Province, China
Xu Wang, Department of Endocrinology, Hai’an People’s Hospital (Hai’an Hospital Affiliated to Nantong University), Nantong 226600, Jiangsu Province, China
Chun-Yan Ge, Department of Nursing, Hai’an People’s Hospital (Hai’an Hospital Affiliated to Nantong University), Nantong 226600, Jiangsu Province, China
Author contributions: Ma JH contributed to data collection, and paper writing; Ma JH, Wang X, and Zhang Y contributed to research design and data analysis; Wang X and Zhang Y contributed to funding application, reviewing and editing, communication coordination, ethical review, copyright and licensing, and follow-up; Ge CY contributed as the corresponding author and supervised the study. All authors have read and approve the final manuscript.
Supported by the 2025 Special Clinical Research Fund Project of Nantong University; and the 2024 Hospital-level Scientific Research Project of Hai’an People’s Hospital.
Institutional review board statement: The research was reviewed and approved by The Hai’an City People’s Hospital (approval No. 2025-L025).
Informed consent statement: All study participants, or their legal guardian, provided informed written consent prior to study enrollment.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
STROBE statement: The authors have read the STROBE Statement-checklist of items, and the manuscript was prepared and revised according to the STROBE Statement-checklist of items.
Data sharing statement: No other data available.
Corresponding author: Chun-Yan Ge, Chief Nurse, Department of Nursing, Hai’an People’s Hospital (Hai’an Hospital Affiliated to Nantong University), No. 17 Zhongba Middle Road, Nantong 226600, Jiangsu Province, China. m18001468751@163.com
Received: March 27, 2026
Revised: April 22, 2026
Accepted: June 11, 2026
Published online: September 15, 2026
Processing time: 151 Days and 6.6 Hours
Revised: April 22, 2026
Accepted: June 11, 2026
Published online: September 15, 2026
Processing time: 151 Days and 6.6 Hours
Core Tip
Core Tip: This study shifts the paradigm of cancer supportive care from symptom-focused management to comorbidity-integrated intervention. By demonstrating that syndrome differentiation nursing simultaneously alleviates chemotherapy toxicity and stabilizes residual renal function in diabetic nephropathy patients with gastric cancer, it provides clinical evidence for the “spleen-kidney co-regulation” theory. The findings advocate for embedding traditional Chinese medicine pattern-based nursing into multidisciplinary co-management of oncology-nephrology complex conditions.