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World J Gastrointest Oncol. May 15, 2026; 18(5): 116776
Published online May 15, 2026. doi: 10.4251/wjgo.v18.i5.116776
Published online May 15, 2026. doi: 10.4251/wjgo.v18.i5.116776
Successful seven-year management of recurrent adult pancreatoblastoma with liver metastasis: A case report
Shui-Guo Tang, Xiang-Ling Wei, Rong-Ji Ye, Hao-Qing Xu, Shu-Hao Shang, Yu-Xuan Han, Lin-Wei Wu, Wu-Zheng Xia, Department of Organ Transplantation, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou 510080, Guangdong Province, China
Wu-Zheng Xia, Department of General Surgery, Guangdong Provincial People’s Hospital Ganzhou Hospital, Ganzhou 341099, Jiangxi Province, China
Co-first authors: Shui-Guo Tang and Xiang-Ling Wei.
Co-corresponding authors: Lin-Wei Wu and Wu-Zheng Xia.
Author contributions: Tang SG and Wei XL collected the case information as co-first authors; Tang SG, Wei XL, Ye RJ, Xu HQ, Shang SH, and Han YX completed the manuscript draft; Wu LW and Xia WZ revised the manuscript as co-corresponding authors; all authors have read and approved the final manuscript.
Supported by Guangzhou Basic and Applied Basic Research Foundation, No. 2025A04J4730; National Natural Science Foundation of China, No. 82470635; and Jiangxi Provincial Natural Science Foundation, No. 20244BAB28028.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors declare no conflict of interest in publishing the manuscript.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Wu-Zheng Xia, MD, PhD, Department of Organ Transplantation, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, No. 106 Zhongshan 2nd Road, Guangzhou 510080, Guangdong Province, China. xiawuzheng@gdph.org.cn
Received: November 24, 2025
Revised: January 27, 2026
Accepted: March 30, 2026
Published online: May 15, 2026
Processing time: 172 Days and 10.9 Hours
Revised: January 27, 2026
Accepted: March 30, 2026
Published online: May 15, 2026
Processing time: 172 Days and 10.9 Hours
Core Tip
Core Tip: We report the 7-year follow-up of an adult pancreatoblastoma patient with liver metastases, emphasizing the importance of multimodal management, including repeated surgeries and targeted therapy. The case highlights the diagnostic utility of positron emission tomography/computed tomography and identifies a novel fibroblast growth factor receptor 1-synaptonemal complex protein 1 gene rearrangement, suggesting a potential target for future therapeutic strategies.