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World J Gastrointest Oncol. Mar 15, 2026; 18(3): 115812
Published online Mar 15, 2026. doi: 10.4251/wjgo.v18.i3.115812
Published online Mar 15, 2026. doi: 10.4251/wjgo.v18.i3.115812
Isolated hepatic tuberculoma: A case report and review of the literature
Dan-Yu Qi, Yu-Chong Zhao, Li-Ping Chen, Department of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China
Author contributions: Qi DY was responsible for conceptualization, data curation, and writing of the original draft; Zhao YC contributed to methodology, investigation, and supervision; Chen LP handled formal analysis, visualization, and review & editing of the manuscript; all authors have read and approved the final manuscript.
Informed consent statement: Informed written consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors declare no conflict of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Li-Ping Chen, MD, Department of Gastroenterology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 13 Hangkong Road, Qiaokou District, Wuhan 430030, Hubei Province, China. lpchen@hust.edu.cn
Received: October 27, 2025
Revised: November 25, 2025
Accepted: December 19, 2025
Published online: March 15, 2026
Processing time: 137 Days and 8.5 Hours
Revised: November 25, 2025
Accepted: December 19, 2025
Published online: March 15, 2026
Processing time: 137 Days and 8.5 Hours
Core Tip
Core Tip: This case report describes a young immunocompetent man with primary hepatic tuberculosis, presenting as an isolated caudate lobe lesion without extrahepatic involvement. Clinical manifestation was atypical, characterized solely by abdominal pain. Radiological findings mimicked a malignant tumor. The final diagnosis was confirmed through endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNA) and polymerase chain reaction. Both blood and liver tissue tuberculosis spot tests were negative, so it should not be solely relied upon for diagnosis. This case highlights the crucial role of EUS-FNA in obtaining diagnosis and successful treatment, emphasizing its value when imaging can not provide a clear diagnosis.