Copyright
©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Feb 15, 2026; 18(2): 115404
Published online Feb 15, 2026. doi: 10.4251/wjgo.v18.i2.115404
Published online Feb 15, 2026. doi: 10.4251/wjgo.v18.i2.115404
Application value of multiphase contrast-enhanced computed tomography radiomics in preoperative evaluation of peritoneal metastasis in gastric cancer
Xiao-Dan Mu, Dong-Xu Ji, De-Qiang Kang, Department of Radiology, Peking University International Hospital, Beijing 102206, China
Co-first authors: Xiao-Dan Mu and Dong-Xu Ji.
Author contributions: Mu XD and Ji DX contributed equally to this study as co-first authors; Mu XD was responsible for study design, radiomics analysis, statistical analysis, manuscript writing; Ji DX was responsible for data collection, validation, manuscript writing; Kang DQ was responsible for study conception, supervision, funding acquisition, manuscript revision; all authors approved the final manuscript.
Institutional review board statement: This study was approved by the Medical Ethics Committee of Peking University International Hospital (Approval No. 2025XJ0193).
Informed consent statement: As a retrospective study using anonymized data, the requirement for informed consent was waived by the ethics committee.
Conflict-of-interest statement: The authors declare that they have no conflicts of interest relevant to this study.
Data sharing statement: The datasets generated and analyzed during the current study are available from the corresponding author upon reasonable request. All data are de-identified to protect patient privacy.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: De-Qiang Kang, MD, Department of Radiology, Peking University International Hospital, No. 1 Shengyuan Road, Zhongguancun Life Science Park, Changping District, Beijing 102206, China. pkuih_rad@126.com
Received: November 4, 2025
Revised: December 3, 2025
Accepted: December 17, 2025
Published online: February 15, 2026
Processing time: 90 Days and 17.4 Hours
Revised: December 3, 2025
Accepted: December 17, 2025
Published online: February 15, 2026
Processing time: 90 Days and 17.4 Hours
Core Tip
Core Tip: Multiphase contrast-enhanced computed tomography radiomics enables non-invasive preoperative prediction of peritoneal metastasis in gastric cancer. In a 200-patient cohort, a combined arterial-venous-delayed model (logistic regression within a leakage-free pipeline) outperformed single-phase models, achieving area under the curve 0.876 with good calibration and decision-curve net benefit. The approach may help triage candidates for staging laparoscopy, reduce unnecessary exploratory procedures, and support individualized treatment planning. Reporting follows IBSI/TRIPOD-AI, with feature robustness, cross-validation, and external temporal testing recommended for future multicenter deployment.