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©The Author(s) 2026. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jan 15, 2026; 18(1): 114648
Published online Jan 15, 2026. doi: 10.4251/wjgo.v18.i1.114648
Published online Jan 15, 2026. doi: 10.4251/wjgo.v18.i1.114648
Colossal well-differentiated liposarcoma of the small bowel mesentery: A case report
Yong Tian, Chuan-Fang Li, Qing-Ming Tian, Song Qiao, Department of Gastrointestinal Surgery, Tongren City People’s Hospital, Tongren 554300, Guizhou Province, China
Guo-Qin Liu, Hemodialysis Center, Tongren Municipal Maternal and Child Health Hospital, Tongren 554300, Guizhou Province, China
Co-first authors: Yong Tian and Guo-Qin Liu.
Co-corresponding authors: Qing-Ming Tian and Song Qiao.
Author contributions: Tian Y and Liu GQ contribute equally to this study as co-first authors; Tian QM and Qiao S contribute equally to this study as co-corresponding authors; Tian Y consulted the literature and wrote the manuscript; Liu GQ studied the literature and made pictures; Li CF, Tian QM and Qiao S operated on the patient and had the idea for this case report; Qiao S checked the manuscript and made the corrections; all authors read and approved the final manuscript.
Informed consent statement: The patient provided a written informed consent form.
Conflict-of-interest statement: There is no conflict of interest associated with any of the senior author or other coauthors contributed their efforts in this manuscript.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Song Qiao, MD, Department of Gastrointestinal Surgery, Tongren City People’s Hospital, No. 120 Middle Section of Taoyuan Avenue, Chuandong Education Park, Tongren 554300, Guizhou Province, China. 13985850520@163.com
Received: September 25, 2025
Revised: October 31, 2025
Accepted: December 4, 2025
Published online: January 15, 2026
Processing time: 109 Days and 9.6 Hours
Revised: October 31, 2025
Accepted: December 4, 2025
Published online: January 15, 2026
Processing time: 109 Days and 9.6 Hours
Core Tip
Core Tip: Well-differentiated small bowel mesenteric liposarcoma (LPS) is rare, with high malignancy, poor prognosis, and high preponderance to local recurrence. The patient underwent complete surgical resection of the tumor, and the weight of the tumor was approximately 11 kg. Both histopathological and fluorescence in situ hybridization examination confirmed that MDM2 amplification, and the small intestine mesenteric well-differentiated LPS was accurate diagnosed.