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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Feb 15, 2025; 17(2): 98803
Published online Feb 15, 2025. doi: 10.4251/wjgo.v17.i2.98803
Published online Feb 15, 2025. doi: 10.4251/wjgo.v17.i2.98803
Metastatic lymph node distribution and pathology correlations in upper and lower gastric cancer patients: A multicenter retrospective study
Xian-Bei Yuan, Gang Sun, Department of General Surgery, No. 967 Hospital of the People's Liberation Army Joint Logistics Support Force, Dalian 116000, Liaoning Province, China
Jun Niu, Department of Trauma Surgery, The No. 967 Hospital of People's Liberation Army Joint Logistics Support Force, Dalian 116000, Liaoning Province, China
Lei Dong, Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian 116000, Liaoning Province, China
Yi Sui, Department of General Surgery, The Fifth People's Hospital of Shenyang, Shenyang 110000, Liaoning Province, China
Yong-Zhu Lv, Department of General Surgery, The Fifth People's Hospital of Dalian, Dalian 116000, Liaoning Province, China
Co-corresponding authors: Gang Sun and Jun Niu.
Author contributions: Yuan XB contributed to the manuscript writing, data collection and analysis; Sun G and Niu J were involved in the conceptualization and supervision of this study; Sui Y, Dong L, Lv YZ and Sui provided multicenter data support. All authors have read and approved the final version to be published.
Institutional review board statement: This study was reviewed and approved by the Medical Ethics Committee of The No. 967 Hospital of PLA Joint Logistics Support Force, the leading unit for this project.
Informed consent statement: The analysis used anonymous clinical data that were obtained after each patient agreed to treatment by written informed consent.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest related to this article.
Data sharing statement: The datasets used and analyzed during the current study are available from the corresponding author on reasonable request.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Gang Sun, MD, PhD, Associate Chief Physician, Associate Professor, Department of General Surgery, The No. 967 Hospital of PLA Joint Logistics Support Force, No. 89 Maolin Street, Dalian 116000, Liaoning Province, China. neomoon@yeah.net
Received: July 6, 2024
Revised: October 17, 2024
Accepted: October 25, 2024
Published online: February 15, 2025
Processing time: 196 Days and 5.8 Hours
Revised: October 17, 2024
Accepted: October 25, 2024
Published online: February 15, 2025
Processing time: 196 Days and 5.8 Hours
Core Tip
Core Tip: Upper gastric cancer (GC) has a significantly greater degree of malignancy than lower GC. In upper GC, the rate of lymph node metastasis was greater in groups Nos. 1, 2, 3 and 7 among the different subtypes. In lower GC, the rate of lymph node metastasis was greater in groups Nos. 3–8. Pathological type, histological grade, pT stage, tumor-node-metastasis (pTNM) stage, and vascular invasion independently influenced the occurrence of lymph node metastasis. Age, pathological type, pT stage, pN stage, pTNM stage, vascular invasion, and absence of adjuvant chemotherapy independently influenced prognosis.