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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Nov 15, 2025; 17(11): 110486
Published online Nov 15, 2025. doi: 10.4251/wjgo.v17.i11.110486
Published online Nov 15, 2025. doi: 10.4251/wjgo.v17.i11.110486
Management of peritoneal metastases from colorectal cancer and small bowel adenocarcinoma in patients with inflammatory bowel disease
Daniel Paramythiotis, Dimitrios Tsavdaris, Dominick Alessandro Sacchet, First Department of Propaedeutic Surgery, University General Hospital of Thessaloniki AHEPA, Aristotle University of Thessaloniki, Thessaloniki 54636, Greece
Georgios Geropoulos, Kyriakos Psarras, Third Department of Surgery, University General Hospital of Thessaloniki AHEPA, Aristotle University of Thessaloniki, Thessaloniki 54636, Greece
Author contributions: Paramythiotis D conceptualized the review topic and designed the structure of the manuscript; Tsavdaris D, Geropoulos G, and Sacchet DA conducted the literature search, analyzed the available data, and drafted the initial manuscript; Psarras K provided critical revisions, contributed to the clinical and methodological interpretation, and ensured accuracy and coherence of the final content; All authors reviewed and approved the final version of the manuscript.
Conflict-of-interest statement: All authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Daniel Paramythiotis, MD, PhD, Full Professor, First Department of Propaedeutic Surgery, University General Hospital of Thessaloniki AHEPA, Aristotle University of Thessaloniki, Street Kyriakidi 1, Thessaloniki 54636, Greece. danosprx@auth.gr
Received: June 9, 2025
Revised: June 26, 2025
Accepted: September 19, 2025
Published online: November 15, 2025
Processing time: 160 Days and 6.7 Hours
Revised: June 26, 2025
Accepted: September 19, 2025
Published online: November 15, 2025
Processing time: 160 Days and 6.7 Hours
Core Tip
Core Tip: Peritoneal metastases in patients with inflammatory bowel disease (IBD) represent a rare but clinically significant complication of IBD-associated colorectal and small bowel cancers. This minireview highlighted the unique challenges in diagnosis, treatment, and prognosis for this population, emphasizing that while cytoreductive surgery with hyperthermic intraperitoneal chemotherapy is feasible, long-term oncological outcomes remain inferior to patients without IBD. This minireview underscored the urgent need for IBD-specific research, refined surveillance strategies, and personalized therapeutic approaches.