©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Nov 15, 2024; 16(11): 4321-4325
Published online Nov 15, 2024. doi: 10.4251/wjgo.v16.i11.4321
Published online Nov 15, 2024. doi: 10.4251/wjgo.v16.i11.4321
Unveiling the clinicopathological enigma of crawling-type gastric adenocarcinoma
Grigorios Christodoulidis, Marina N Kouliou, Konstantinos E Koumarelas, Department of General Surgery, University Hospital of Larissa, University of Thessaly, Biopolis Campus, Larissa 41110, Greece
Sara E Agko, Department of Orthopedic, University Hospital of Larissa, Larissa 41110, Greece
Author contributions: Christodoulidis G, Agko SE, Koumarelas KE and Kouliou MN contributed to this paper; Christodoulidis G designed the overall concept and outline of the manuscript; Christodoulidis G, Agko SE, Koumarelas KE and Kouliou MN contributed to the discussion and design of the manuscript; Christodoulidis G, Agko SE, Koumarelas KE and Kouliou MN contributed to the writing, editing the manuscript, and review of the literature.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Corresponding author: Grigorios Christodoulidis, MD, PhD, Academic Editor, Department of General Surgery, University Hospital of Larissa, University of Thessaly, Biopolis Campus, Mezourlo, Larissa 41110, Greece. gregsurg@yahoo.gr
Received: March 23, 2024
Revised: May 14, 2024
Accepted: June 11, 2024
Published online: November 15, 2024
Processing time: 215 Days and 15.2 Hours
Revised: May 14, 2024
Accepted: June 11, 2024
Published online: November 15, 2024
Processing time: 215 Days and 15.2 Hours
Core Tip
Core Tip: Crawling-type adenocarcinoma has specific features, such as irregularly fused glands and low-grade cellular atypia, resembling intestinal metaplasia. Given this, precise attention to its histological characteristics is crucial when diagnosing “crawling-type” adenocarcinoma (CRA). Early detection of CRA is challenging which leads to the importance of the detection of molecular markers and thorough biopsy analysis for accurate classification and clinical management strategies.