Letter to the Editor
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Aug 15, 2022; 14(8): 1597-1599
Published online Aug 15, 2022. doi: 10.4251/wjgo.v14.i8.1597
Colitis and colorectal tumors should be further explored and differentiated
Dong-Hui Xu, Bo Zhou, Zhi-Peng Li, Lian-Ping He, Xin-Juan Wang
Dong-Hui Xu, Bo Zhou, Zhi-Peng Li, Lian-Ping He, Xin-Juan Wang, School of Medicine, Taizhou University, Jiaojiang 318000, Zhejiang Province, China
Author contributions: Wang XJ and He LP conceived of the presented idea and provided critical feedback to the final manuscript, revised the manuscript and approved the main conceptual ideas and outline; Xu DH, Zhou B, and Li ZP wrote the manuscript; all authors provided final edits and approved the manuscript.
Supported by the General Research Project of Education Department of Zhejiang Province, No. Y202146955; and the Second Batch of Research Projects on Teaching Reform in the 13th Five-year Plan of Zhejiang Province, No. Jg20190460.
Conflict-of-interest statement: All authors declare no potential conflicts of interest with respect to the research, authorship, and/or publication of this article. All other authors have read the manuscript and have agreed to submit it in its current form for consideration for publication in the world Journal of Gastrointestinal Oncology.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Xin-Juan Wang, MD, Senior Researcher, School of Medicine, Taizhou University, No. 1139 Shifu Avenue, Jiaojiang District, Taizhou 318000, Zhejiang Province, China. wxjyxy@tzc.edu.cn
Received: April 1, 2022
Peer-review started: April 1, 2022
First decision: May 1, 2022
Revised: May 1, 2022
Accepted: July 16, 2022
Article in press: July 16, 2022
Published online: August 15, 2022
Processing time: 131 Days and 5.4 Hours
Core Tip

Core Tip: Among genetic factors, the deletion or mutation of some tumor suppressor genes can lead to colorectal tumors. Non-genetic factors are also associated with the development of colorectal tumors. The underlying disease can be a risk factor for colorectal tumors. There are significant gender differences in the occurrence and development of colorectal tumors. These all suggest that colorectal tumors are not only caused by ulcerative colitis, and we suggest further exploration and differentiation between colitis and colorectal tumors.