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Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Aug 15, 2021; 13(8): 758-771
Published online Aug 15, 2021. doi: 10.4251/wjgo.v13.i8.758
Metabolism-associated genes in occurrence and development of gastrointestinal cancer: Latest progress and future prospect
Yan-Dong Miao, Lin-Jie Mu, Deng-Hai Mi
Yan-Dong Miao, Deng-Hai Mi, The First Clinical Medical College, Lanzhou University, Lanzhou 730000, Gansu Province, China
Lin-Jie Mu, The First Affiliated Hospital, Kunming Medical University, Kunming 650000, Yunnan Province, China
Deng-Hai Mi, Dean’s Office, Gansu Academy of Traditional Chinese Medicine, Lanzhou 730000, Gansu Province, China
Author contributions: Mi DH designed the research; Miao YD and Mu LJ performed the writing and data analysis, and prepared the figures and tables; Miao YD and Mu LJ contributed equally to this work; all authors approved the final manuscript.
Conflict-of-interest statement: There is no conflict of interest associated with any of the senior author or other coauthors who contributed their efforts in this manuscript.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Deng-Hai Mi, MD, Chief Doctor, Dean, Professor, The First Clinical Medical College, Lanzhou University, No. 1 Donggang West Road, Chengguan District, Lanzhou 730000, Gansu Province, China. mi.dh@outlook.com
Received: January 22, 2021
Peer-review started: January 22, 2021
First decision: February 24, 2021
Revised: February 27, 2021
Accepted: June 23, 2021
Article in press: June 23, 2021
Published online: August 15, 2021
Processing time: 203 Days and 21.7 Hours
Core Tip

Core Tip: Metabolic reprogramming is one of the hallmarks of cancer and is intricately related to tumorigenesis. Many metabolic genes are involved in the occurrence and development of gastrointestinal (GI) cancer. This state-of-the-art review comprehensively describes the latest progress and prospects into the different molecular mechanisms of metabolism-associated genes involved in the occurrence and development of GI cancer.