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©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. May 15, 2020; 12(5): 526-534
Published online May 15, 2020. doi: 10.4251/wjgo.v12.i5.526
Published online May 15, 2020. doi: 10.4251/wjgo.v12.i5.526
Identification of integrin β6 gene promoter and analysis of its transcription regulation in colon cancer cells
Wei Niu, Jun Niu, Zheng-Chuan Niu, Cheng Peng, Xue-Qing Zou, Department of Hepatobiliary Surgery, Qilu Hospital, Shandong University, Jinan 250012, Shandong Province, China
Qi-Yu Bo, Department of Nursing, Qilu Hospital, Shandong University, Jinan 250012, Shandong Province, China
Zhao-Yang Zhang, Department of Emergency Surgery, Qilu Hospital, Shandong University, Jinan 250012, Shandong Province, China
Author contributions: Niu W and Bo QY contributed equally to this article and should be considered as co-first authors; Niu W and Bo QY designed the experiments; Zhang ZY drafted the work and collected the data; Niu J, Niu ZC, Peng C, Zou XQ, and Zhang ZY analysed and interpreted the data and wrote the article.
Supported by National Sciences Foundation of Shandong Province , No. ZR2014HM101 .
Institutional review board statement: The study was reviewed and approved by the Institutional Review Board of Qilu Hospital, Shandong University.
Conflict-of-interest statement: The authors declare no conflicts of interest related to this manuscript.
Data sharing statement: No additional data are available.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Corresponding author: Zhao-Yang Zhang, MD, Associate Chief Physician, Associate Professor, Department of Emergency Surgery, Qilu Hospital, Shandong University, No. 44, Wenhua Xi Road, Jinan 250012, Shandong Province, China.drzzyang@163.com
Received: January 20, 2020
Peer-review started: January 20, 2020
First decision: March 24, 2020
Revised: March 29, 2020
Accepted: April 15, 2020
Article in press: April 15, 2020
Published online: May 15, 2020
Processing time: 115 Days and 0.7 Hours
Peer-review started: January 20, 2020
First decision: March 24, 2020
Revised: March 29, 2020
Accepted: April 15, 2020
Article in press: April 15, 2020
Published online: May 15, 2020
Processing time: 115 Days and 0.7 Hours
Core Tip
Core tip: In this paper, the transcription regulation of integrin β6 is described and the region of core promoter region is identified. Meanwhile, the mechanism of transcription regulation of integrin β6 is explored.