Giz N, Epshtein J, Savin B, Meir K, Slae M. Presentation and endoscopic resection technique of neonatal esophageal choristoma: A case report. World J Gastrointest Oncol 2026; 18(3): 113851 [DOI: 10.4251/wjgo.v18.i3.113851]
Corresponding Author of This Article
Mordechai Slae, MD, Assistant Professor, Pediatric Gastroenterology Unit, Hadassah-Hebrew University Medical Center, Kalman Yaacov Man, POB 12000, Jerusalem 9112001, Israel. mord@hadassah.org.il
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Mar 15, 2026 (publication date) through Mar 12, 2026
Times Cited of This Article
Times Cited (0)
Journal Information of This Article
Publication Name
World Journal of Gastrointestinal Oncology
ISSN
1948-5204
Publisher of This Article
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Share the Article
Giz N, Epshtein J, Savin B, Meir K, Slae M. Presentation and endoscopic resection technique of neonatal esophageal choristoma: A case report. World J Gastrointest Oncol 2026; 18(3): 113851 [DOI: 10.4251/wjgo.v18.i3.113851]
World J Gastrointest Oncol. Mar 15, 2026; 18(3): 113851 Published online Mar 15, 2026. doi: 10.4251/wjgo.v18.i3.113851
Presentation and endoscopic resection technique of neonatal esophageal choristoma: A case report
Neriya Giz, Julia Epshtein, Boris Savin, Karen Meir, Mordechai Slae
Neriya Giz, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem 9112001, Israel
Julia Epshtein, Boris Savin, Department of Gastroenterology, Hadassah-Hebrew University Medical Center, Jerusalem 9112001, Israel
Karen Meir, Department of Pathology, Hadassah-Hebrew University Medical Center, Jerusalem 9112001, Israel
Mordechai Slae, Pediatric Gastroenterology Unit, Hadassah-Hebrew University Medical Center, Jerusalem 9112001, Israel
Author contributions: Giz N, Meir K, and Slae M conducted the literature review and contributed to manuscript writing; Epshtein J, Savin B, and Slae M planned and performed the endoscopic intervention; Meir K conducted the pathology analysis. All authors approved the final version to publish.
Informed consent statement: The patient’s caregiver provided written informed consent for both the procedure and the publication.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Mordechai Slae, MD, Assistant Professor, Pediatric Gastroenterology Unit, Hadassah-Hebrew University Medical Center, Kalman Yaacov Man, POB 12000, Jerusalem 9112001, Israel. mord@hadassah.org.il
Received: September 8, 2025 Revised: November 18, 2025 Accepted: January 4, 2026 Published online: March 15, 2026 Processing time: 188 Days and 14.7 Hours
Abstract
BACKGROUND
Esophageal choristoma is an exceptionally rare congenital non-malignant mass which may present with a range of symptoms and severity according to size, growth and location.
CASE SUMMARY
In this article, we describe the case of a 12-day-old patient with an esophageal choristoma. The patient presented to the hospital with intermittent episodes of protrusion of unidentified tissue through the mouth, along with apneic episodes and failure to thrive. The mass was subsequently identified as originating from the upper esophagus. Given the mass size and the severity of symptoms, a decision was made to perform a complete endoscopic mucosal resection, the first procedure of its kind. The intervention was successful, with no complications, and the infant achieved full recovery. The endoscopic approach chosen for this case is presented in detail along with the existing literature on the presentation and treatment of similar cases.
CONCLUSION
Endoscopic mucosal resection is feasible and curative in neonatal esophageal symptomatic masses.
Core Tip: Esophageal choristoma is an extremely rare congenital anomaly in neonates. This case report presents the clinical features, challenging yet successful diagnosis, and definitive treatment of a large esophageal choristoma in a 12-day-old infant. Notably, it describes the first documented case of complete endoscopic mucosal resection performed in a neonate using a slim endoscope, demonstrating endoscopic mucosal resection as a safe, effective, and minimally invasive curative option for pediatric esophageal masses.
