Guo AW, Liu YS, Li H, Yuan Y, Li SX. Ewing sarcoma of the ileum with wide multiorgan metastases: A case report and review of literature. World J Gastrointest Oncol 2022; 14(8): 1585-1593 [PMID: 36160753 DOI: 10.4251/wjgo.v14.i8.1585]
Corresponding Author of This Article
Hang Li, MD, Doctor, Department of Radiology, Affiliated Hospital of Medical School, University of Electronic Science and Technology of China, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, No. 32 Second Section of First Ring Road, Qingyang District, Chengdu 610072, Sichuan Province, China. lihang111222@126.com
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Case Report
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastrointest Oncol. Aug 15, 2022; 14(8): 1585-1593 Published online Aug 15, 2022. doi: 10.4251/wjgo.v14.i8.1585
Ewing sarcoma of the ileum with wide multiorgan metastases: A case report and review of literature
Ai-Wen Guo, Yi-Sha Liu, Hang Li, Yi Yuan, Si-Xun Li
Ai-Wen Guo, Hang Li, Yi Yuan, Si-Xun Li, Department of Radiology, Affiliated Hospital of Medical School, University of Electronic Science and Technology of China, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu 610072, Sichuan Province, China
Ai-Wen Guo, Department of Radiology, Chengdu Women's and Children's Central Hospital, School of Medicine, Chengdu 611731, Sichuan Province, China
Yi-Sha Liu, Department of Pathology, Affiliated Hospital of Medical School, University of Electronic Science and Technology of China, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, Chengdu 610072, Sichuan Province, China
Author contributions: Li H and Guo AW were responsible for the coordination of the project and contributed to the study design; Li H, Guo AW, Yuan Y and Liu YS collected, analyzed the data and edited the manuscript. Yuan Y and Li SX followed up the patient; Yuan Y and Li H supervised the study and reviewed this manuscript; All authors have read and approved the final manuscript.
Informed consent statement: The patient involved in this study gave his written consent authorizing use and disclosure of his protected health information.
Conflict-of-interest statement: All authors report no relevant conflict of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklis (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Hang Li, MD, Doctor, Department of Radiology, Affiliated Hospital of Medical School, University of Electronic Science and Technology of China, Sichuan Academy of Medical Sciences and Sichuan Provincial People's Hospital, No. 32 Second Section of First Ring Road, Qingyang District, Chengdu 610072, Sichuan Province, China. lihang111222@126.com
Received: March 13, 2022 Peer-review started: March 13, 2022 First decision: April 17, 2022 Revised: May 2, 2022 Accepted: July 11, 2022 Article in press: July 11, 2022 Published online: August 15, 2022 Processing time: 150 Days and 12.3 Hours
Abstract
BACKGROUND
Ewing sarcoma (ES) is an aggressive small round cell tumor that usually occurs in younger children and young adults but rarely in older patients. Its occurrence in elderly individuals is rare. ES of the ileum with wide multiorgan metastases is rarely reported and difficult to distinguish radiologically from other gastrointestinal tract tumors.
CASE SUMMARY
A 53-year-old man presented with right lower quadrant pain for 2 wk. Computed tomography results showed a heterogeneous mass within the ileum and widespread multiorgan metastases. This mass was biopsied, and pathological examination of the resected specimen revealed features consistent with an extraskeletal ES.
CONCLUSION
This case emphasizes the importance of recognizing this rare presentation in the small intestine to broaden the differential diagnosis of adult intraabdominal tumors.
Core Tip: Ewing’s sarcoma (EOES) originating in the ileum with wide multiorgan metastases is rare and easily misdiagnosed. When a small intestine mass accompanied by calcification and wide multiorgan metastases is seen on computed tomography, a suspicion of EOES should not be overlooked. Together with previous reports, this case expands knowledge regarding the spectrum of tumors in the small intestine.
