Letter to the Editor
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Oncol. Jan 15, 2022; 14(1): 362-365
Published online Jan 15, 2022. doi: 10.4251/wjgo.v14.i1.362
Liquid biopsy: Precise diagnosis and therapy for cholangiocarcinoma
Si-Qin Wang, Chu-Xing Chai, Bi-Rong Wang, Feng Zhu, Dan Shang, Min Li
Si-Qin Wang, Feng Zhu, Dan Shang, Department of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China
Chu-Xing Chai, Min Li, Department of Hepatobiliary Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, Hubei Province, China
Bi-Rong Wang, Department of Breast and Thyroid Surgery, Wuhan Fourth Hospital; Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China
Author contributions: Wang SQ, Chai CX and Wang BR contributed equally to this work and drafted the manuscript; Chai CX and Li M revised the manuscript; Wang SQ, Chai CX, Wang BR and Zhu F collected the references; Li M and Shang D designed the work; all authors approved the final version.
Supported by Wuhan Municipal Health Commission, No. WX14B22; and National Natural Science Foundation of China, No. 81874208 and No. 81700425.
Conflict-of-interest statement: The authors declare no conflicts of interest for this article.
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Dan Shang, MD, PhD, Associate Professor, Department of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan 430022, Hubei Province, China. danshang@hust.edu.cn
Received: June 12, 2021
Peer-review started: June 12, 2021
First decision: July 16, 2021
Revised: July 19, 2021
Accepted: November 26, 2021
Article in press: November 26, 2021
Published online: January 15, 2022
Processing time: 212 Days and 20.3 Hours
Abstract

The following letter to the editor highlights the review titled “Liquid biopsy in cholangiocarcinoma: Current status and future perspective” in World J Gastrointest Oncol 2021; 13: 332-350. It is necessary to realize individualized therapy to improve the clinical prognosis of patients with cholangiocarcinoma.

Keywords: Liquid biopsy; Cholangiocarcinoma; Diagnosis; Therapy; Precision medicine

Core Tip: Cholangiocarcinoma (CCA) is an aggressive biliary malignancy, and existing clinical tools cannot improve survival rates. The major goal of this letter is to stress the fascinating promise and challenge of liquid biopsy in the diagnosis and therapy of patients with CCA.