©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Apr 16, 2017; 9(4): 153-161
Published online Apr 16, 2017. doi: 10.4253/wjge.v9.i4.153
Published online Apr 16, 2017. doi: 10.4253/wjge.v9.i4.153
Non-functioning pancreatic neuroendocrine tumors: Surgery or observation?
Yehonatan Bar-Moshe, Haggi Mazeh, Department of Surgery, Hadassah-Hebrew University Medical Center, Mount Scopus, Jerusalem 91240, Israel
Simona Grozinsky-Glasberg, Neuroendocrine Tumor Unit, Hadassah-Hebrew University Medical Center, Jerusalem 91240, Israel
Author contributions: Bar-Moshe Y, Mazeh H and Grozinsky-Glasberg S collected, reviewed, and summarized the data.
Conflict-of-interest statement: The authors report no financial or ethical conflicts of interest.
Correspondence to: Dr. Haggi Mazeh, Department of Surgery, Hadassah-Hebrew University Medical Center, Mount Scopus, PO Box 24035, Jerusalem 91240, Israel. hmazeh@hadassah.org.il
Telephone: +972-2-5844550 Fax: +972-2-5844584
Received: August 28, 2016
Peer-review started: August 30, 2016
First decision: September 27, 2016
Revised: October 23, 2016
Accepted: January 11, 2017
Article in press: January 12, 2017
Published online: April 16, 2017
Processing time: 229 Days and 3.9 Hours
Peer-review started: August 30, 2016
First decision: September 27, 2016
Revised: October 23, 2016
Accepted: January 11, 2017
Article in press: January 12, 2017
Published online: April 16, 2017
Processing time: 229 Days and 3.9 Hours
Core Tip
Core tip: Nonfunctional pancreatic neuroendocrine tumors are increasingly diagnosed. Controversy exists regarding their optimal management. Expectant management in small size, low grade, incidentally diagnosed nonfunctional pancreatic neuroendocrine tumors has been suggested as an optional treatment. The aim of this study is to review the available literature addressing nonfunctional pancreatic neuroendocrine tumors, with an emphasis on surgical management controversies.