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World J Gastrointest Endosc. Apr 16, 2026; 18(4): 117233
Published online Apr 16, 2026. doi: 10.4253/wjge.v18.i4.117233
Published online Apr 16, 2026. doi: 10.4253/wjge.v18.i4.117233
Bronchogenic cysts treated with submucosal tunneling endoscopic resection and natural orifice transluminal endoscopy: Two case reports and review of literature
Jie-Min Ma, Chen-Guang Ji, Li Liu, Kai-Ge Yin, Endoscopy Center, Luquan Campus, The Second Hospital of Hebei Medical University, Shijiazhuang 050000, Hebei Province, China
Co-first authors: Jie-Min Ma and Chen-Guang Ji.
Co-corresponding authors: Li Liu and Kai-Ge Yin.
Author contributions: Liu L and Yin KG performed the endoscopic procedures and provided critical technical guidance, revised the manuscript for important intellectual content and they contributed equally to this manuscript and are co-corresponding authors; Ma JM and Ji CG collected the clinical data, reviewed the literature, drafted the manuscript, and conducted patient follow-up and they contributed equally to this manuscript and are co-first authors. All authors have read and approved the final manuscript.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Corresponding author: Li Liu, MD, Chief Physician, Professor, Endoscopy Center, Luquan Campus, The Second Hospital of Hebei Medical University, No. 501 Huai’an West Road, Shijiazhuang 050000, Hebei Province, China. loraliu@163.com
Received: December 2, 2025
Revised: January 19, 2026
Accepted: March 13, 2026
Published online: April 16, 2026
Processing time: 132 Days and 18.6 Hours
Revised: January 19, 2026
Accepted: March 13, 2026
Published online: April 16, 2026
Processing time: 132 Days and 18.6 Hours
Core Tip
Core Tip: Mediastinal bronchogenic cysts adjacent to the esophagus can closely resemble submucosal esophageal lesions on preoperative imaging, posing diagnostic challenges. We describe two cases managed using a transesophageal mediastinal tunneling technique that integrates submucosal tunneling endoscopic resection with natural orifice transluminal endoscopic surgery. This innovative, minimally invasive approach allows precise intraoperative identification, complete en bloc cyst excision, and excellent postoperative recovery while avoiding thoracotomy.