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©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Sep 16, 2025; 17(9): 109144
Published online Sep 16, 2025. doi: 10.4253/wjge.v17.i9.109144
Published online Sep 16, 2025. doi: 10.4253/wjge.v17.i9.109144
Endoscopic submucosal dissection for early gastrointestinal malignancies: Current state and future perspectives
Sandip Pal, Gourab Bhaduri, Department of Gastroenterology and Hepatology, Narayana Health, Kolkata 700094, West Bengal, India
Author contributions: Pal S provided the pictures of endoscopic submucosal dissection procedures, performed and revised to give a final shape to the manuscript; Bhaduri G wrote the draft of the article and collected existing data for the literature review; Pal S and Bhaduri G they contributed equally to this article, they are the co-first authors of this manuscript; and all authors thoroughly reviewed and endorsed the final manuscript.
Conflict-of-interest statement: All the authors report no relevant conflicts of interest for this article.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Sandip Pal, MD, Consultant Interventional Gastroenterologist and Hepatologist, Department of Gastroenterology and Hepatology, Narayana Health, Upohar, Tower 6, Flat 103 Chak Garia, Panchasayar, Kolkata 700094, West Bengal, India.
Revised: May 28, 2025
Accepted: July 17, 2025
Published online: September 16, 2025
Processing time: 135 Days and 10.4 Hours
Accepted: July 17, 2025
Published online: September 16, 2025
Processing time: 135 Days and 10.4 Hours
Core Tip
Core Tip: This article provides a comprehensive overview of endoscopic submucosal dissection for early esophageal, gastric, and colon cancers, detailing technical approaches, common pitfalls, and current evidence. This review also discusses the management of common procedural complications. Gastroenterologists can use this guide to improve outcomes and optimize the application of endoscopic submucosal dissection in managing early gastrointestinal cancer.