Case Report
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
World J Gastrointest Endosc. Aug 16, 2025; 17(8): 109399
Published online Aug 16, 2025. doi: 10.4253/wjge.v17.i8.109399
Detachable over-the-scope clip for colon defects in the trans intestinal natural orifice transluminal endoscopic cholecystolithotomy: A case report
Pei Li, Rong-Rong Ding, Jiang Liu, Ming-Qing Zhang, Yan Liu
Pei Li, Department of Gastroenterology, The 909th Hospital, School of Medicine, Xiamen University, Fujian Province 363000, Fujian Province, China
Rong-Rong Ding, Jiang Liu, Ming-Qing Zhang, Yan Liu, Department of Gastroenterology, The 909th Hospital, School of Medicine, Xiamen University, Zhangzhou 363000, Fujian Province, China
Co-first authors: Pei Li and Rong-Rong Ding.
Author contributions: Li P organized the case and wrote manuscript; Ding RR contributed to administered therapy for patient and wrote manuscript; Liu J contributed to supervised writing of manuscript; Zhang MQ contributed to performed surgical procedures for patient; Liu Y contributed to drafting the manuscript.
Supported by Natural Science Foundation of Fujian Province, China, No. 2021J01545.
Informed consent statement: Written informed consent was obtained from the patient for publication of this report and any accompanying images.
Conflict-of-interest statement: All authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
CARE Checklist (2016) statement: The authors have read the CARE Checklist (2016), and the manuscript was prepared and revised according to the CARE Checklist (2016).
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Yan Liu, Research Fellow, Department of Gastroenterology, The 909th Hospital, School of Medicine, Xiamen University, No. 269 Zhanghua Middle Road, Zhangzhou 363000, Fujian Province, China. 514461566@qq.com
Received: May 12, 2025
Revised: May 30, 2025
Accepted: June 27, 2025
Published online: August 16, 2025
Processing time: 97 Days and 18.1 Hours
Core Tip

Core Tip: In response to clinical requirements, ongoing efforts are being made to investigate the utilization of anastomotic or metal clips for the closure of various full-thickness defects in the mucosa of the digestive tract. Here, we present the case of a 51-year-old patient who underwent transintestinal natural orifice transluminal endoscopic cholecystolithotomy. The sigmoid incision was sealed using a detachable over-the-scope clip (D-OTSC), which was subsequently extracted during enteroscopy one month postoperatively. We believe that the D-OTSC is a viable option for closing colon defects ranging from 1 cm to 2 cm.