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World J Gastrointest Endosc. Jul 16, 2025; 17(7): 107168
Published online Jul 16, 2025. doi: 10.4253/wjge.v17.i7.107168
Innovative schemes of colonoscopy bowel preparation with oral lactulose: Optimizing traditional standards to improve colonoscopy quality
Josué Aliaga Ramos, Danilo Carvalho, Vitor Nunes Arantes
Josué Aliaga Ramos, Department of Gastroenterology, Hospital José Agurto Tello-Chosica, Lima 15, Peru
Josué Aliaga Ramos, Service of Gastroenterology, Clinica Madre Zoraida, Lima 15, Peru
Josué Aliaga Ramos, Digestive Endoscopy, Unit Hospital San Juan de Matucana, Lima 15, Peru
Danilo Carvalho, Endoscopy, Federal University of Minas Gerais, Belo Horizonte 30130-100, Minas Gerais, Brazil
Vitor Nunes Arantes, Endoscopy Unit, Alfa Institute of Gastroenterology, School of Medicine, Federal University of Minas Gerais, Belo Horizonte 30130-100, Minas Gerais, Brazil
Vitor Nunes Arantes, Endoscopy Unit, Mater Dei Contorno Hospital, Belo Horizonte 30110062, Minas Gerais, Brazil
Author contributions: Aliaga Ramos J, Arantes VN and Carvalho D performed the designed the research study; Aliaga Ramos J, Arantes VN and Carvalho D performed the research; Aliaga Ramos J, Arantes VN and Carvalho D performed the project administration; Aliaga Ramos J, Arantes VN and Carvalho D performed the writing–original draft; Aliaga Ramos J, Arantes VN and Carvalho D performed the writing–review & editing.
Conflict-of-interest statement: The authors declare that they have no conflict of interest.
Open Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Corresponding author: Josué Aliaga Ramos, MD, Department of Gastroenterology, Hospital José Agurto Tello-Chosica, 229 Walter Stubbs Street, Lima-Peru, Lima 15, Peru. arjosue3000@gmail.com
Received: March 17, 2025
Revised: April 26, 2025
Accepted: May 29, 2025
Published online: July 16, 2025
Processing time: 114 Days and 10.3 Hours
Core Tip

Core Tip: Bowel preparation is critical for high-quality colonoscopy. Polyethylene glycol is considered the gold standard for bowel preparation, however the need for high volumes impairs patient’s tolerance. The oral lactulose-based scheme has emerged as a new alternative for colonoscopy preparation with a low cost, widely accessible to the general population and with optimal efficacy, safety and tolerability profiles.